HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: SGK2 (Q9HBY8)
Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2)
Gene: SGK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25852190
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 367
+	Hs
		681735 TCPE_HUMAN (1-541): 0: 635: 100.00		AKT1_HUMAN (6-359): 3.45e-151: 436: 47.62
+	Hs
		821353 TCPE_HUMAN (1-541): 0: 635: 100.00		SGK3_HUMAN (9-364): 7.87e-146: 423: 67.69
+	Hs
		821449 TCPE_HUMAN (1-541): 0: 635: 100.00		KS6B2_HUMAN (27-361): 4.56e-146: 423: 45.29
+	Hs
		826897 TCPG_HUMAN (14-540): 0: 572: 33.15		SGK2_HUMAN (1-367): 5.99e-163: 462: 100.00
+	Hs
		1306691 TCPH_HUMAN (12-539): 0: 570: 29.64		SGK2_HUMAN (1-367): 5.99e-163: 462: 100.00
+	Dm
		1180659 Q7KKI0_DROME (5-533): 0: 582: 71.46		AKT1_DROME (28-365): 1.57e-151: 442: 49.26
+	Dm
		1213398 Q9VHL2_DROME (14-541): 0: 577: 28.14		AKT1_DROME (28-365): 1.57e-151: 442: 49.26
+	Hs
		681738 TCPG_HUMAN (14-540): 0: 572: 33.15		AKT1_HUMAN (6-359): 3.45e-151: 436: 47.62
+	Hs
		573486 TCPA_HUMAN (26-541): 0: 545: 32.08		SGK2_HUMAN (1-367): 5.99e-163: 462: 100.00
+	Hs
		681999 TCPH_HUMAN (12-539): 0: 570: 29.64		AKT1_HUMAN (6-359): 3.45e-151: 436: 47.62
+	Hs
		826928 TCPG_HUMAN (14-540): 0: 572: 33.15		KS6B2_HUMAN (27-361): 4.56e-146: 423: 45.29
+	Hs
		1306721 TCPH_HUMAN (12-539): 0: 570: 29.64		KS6B2_HUMAN (27-361): 4.56e-146: 423: 45.29
+	Hs
		573141 TCPA_HUMAN (26-541): 0: 545: 32.08		AKT1_HUMAN (6-359): 3.45e-151: 436: 47.62
+	Hs
		573515 TCPA_HUMAN (26-541): 0: 545: 32.08		KS6B2_HUMAN (27-361): 4.56e-146: 423: 45.29
+	Hs
		821177 TCPE_HUMAN (1-541): 0: 635: 100.00		KPCZ_HUMAN (34-357): 1.99e-96: 300: 45.21
+	Dm
		1180660 Q7KKI0_DROME (5-533): 0: 582: 71.46		Q94533_DROME (18-357): 2.18e-98: 302: 46.09
+	Dm
		1213403 Q9VK69_DROME (36-533): 1.12e-109: 338: 41.39		AKT1_DROME (28-365): 1.57e-151: 442: 49.26
+	Hs
		681747 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		AKT1_HUMAN (6-359): 3.45e-151: 436: 47.62
+	Hs
		843210 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		KS6A1_HUMAN (13-338): 1.87e-104: 325: 25.52
+	Dm
		1276810 Q9VK69_DROME (36-533): 1.12e-109: 338: 41.39		Q94533_DROME (18-357): 2.18e-98: 302: 46.09