HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: KS6B2 (Q9UBS0)
Ribosomal protein S6 kinase beta-2 (S6K-beta-2) (S6K2) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 2) (P70S6K2) (p70-S6K 2) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14B) (p70 ribosomal S6 kinase beta) (S6K-beta) (p70 S6 kinase beta) (p70 S6K-beta) (p70 S6KB) (p70-beta)
Gene: RPS6KB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25324306
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 541 Hs			1 482
+	Hs
		826928 TCPG_HUMAN (14-540): 0: 572: 33.15		KS6B2_HUMAN (1-482): 0: 531: 100.00
+	Hs
		1306721 TCPH_HUMAN (12-539): 0: 570: 29.64		KS6B2_HUMAN (1-482): 0: 531: 100.00
+	Hs
		681735 TCPE_HUMAN (1-541): 0: 635: 100.00		AKT1_HUMAN (5-391): 6.01e-153: 445: 39.19
+	Hs
		573515 TCPA_HUMAN (26-541): 0: 545: 32.08		KS6B2_HUMAN (1-482): 0: 531: 100.00
+	Hs
		568585 TCPE_HUMAN (1-541): 0: 635: 100.00		KAPCA_HUMAN (31-387): 1.3e-144: 419: 34.17
+	Dm
		1180660 Q7KKI0_DROME (5-533): 0: 582: 71.46		Q94533_DROME (43-480): 1.84e-161: 467: 63.24
+	Dm
		1180659 Q7KKI0_DROME (5-533): 0: 582: 71.46		AKT1_DROME (19-395): 5.26e-150: 442: 39.37
+	Dm
		1213398 Q9VHL2_DROME (14-541): 0: 577: 28.14		AKT1_DROME (19-395): 5.26e-150: 442: 39.37
+	Hs
		681738 TCPG_HUMAN (14-540): 0: 572: 33.15		AKT1_HUMAN (5-391): 6.01e-153: 445: 39.19
+	Hs
		681999 TCPH_HUMAN (12-539): 0: 570: 29.64		AKT1_HUMAN (5-391): 6.01e-153: 445: 39.19
+	Hs
		573141 TCPA_HUMAN (26-541): 0: 545: 32.08		AKT1_HUMAN (5-391): 6.01e-153: 445: 39.19
+	Hs
		821353 TCPE_HUMAN (1-541): 0: 635: 100.00		SGK3_HUMAN (46-393): 3.33e-94: 295: 45.00
+	Dm
		1180668 Q7KKI0_DROME (5-533): 0: 582: 71.46		Q9VR61_DROME (18-403): 5.76e-91: 297: 24.44
+	Hs
		843420 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		KS6B2_HUMAN (1-482): 0: 531: 100.00
+	Dm
		1276810 Q9VK69_DROME (36-533): 1.12e-109: 338: 41.39		Q94533_DROME (43-480): 1.84e-161: 467: 63.24
+	Dm
		1213403 Q9VK69_DROME (36-533): 1.12e-109: 338: 41.39		AKT1_DROME (19-395): 5.26e-150: 442: 39.37
+	Hs
		681747 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		AKT1_HUMAN (5-391): 6.01e-153: 445: 39.19
+	Hs
		568593 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		KAPCA_HUMAN (31-387): 1.3e-144: 419: 34.17
+	Hs
		843210 TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80		KS6A1_HUMAN (5-380): 2.15e-105: 331: 25.19