HitPredict

Interactor 1: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL

Interactor 2: DIRA2 (Q96HU8)
GTP-binding protein Di-Ras2 (EC 3.6.5.-) (Distinct subgroup of the Ras family member 2)
Gene: DIRAS2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	32161311
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~VHL
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 213 Hs			1 199
+	Hs
		822860 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		RAB1B_HUMAN (2-197): 8.45e-80: 238: 29.35
+	Hs
		822579 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		RB11A_HUMAN (3-197): 1.29e-75: 228: 26.79
+	Hs
		822564 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		RAB14_HUMAN (3-196): 4.19e-75: 226: 23.70
+	Hs
		822584 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		RAP1A_HUMAN (7-173): 2.59e-46: 152: 45.83
+	Hs
		822796 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		RIT1_HUMAN (5-172): 9e-33: 119: 36.91