Interactor 1: VHL (P40338)
von Hippel-Lindau disease tumor suppressor (pVHL)
Gene: VHL

Interactor 2: EGLN1 (Q91YE3)
Egl nine homolog 1 (EC 1.14.11.29) (Hypoxia-inducible factor prolyl hydroxylase 2) (HIF-PH2) (HIF-prolyl hydroxylase 2) (HPH-2) (Prolyl hydroxylase domain-containing protein 2) (PHD2) (SM-20)
Gene: EGLN1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 26215701
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0014069 - postsynaptic density
GO:0098978 - glutamatergic synapse
GO:0140252 - regulation protein catabolic process at postsynapse
GO:1902072 - negative regulation of hypoxia-inducible factor-1alpha signaling pathway
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 181
Mm

1 400
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025