HitPredict

Interactor 1: BMP5 (P49003)
Bone morphogenetic protein 5 (BMP-5)
Gene: BMP5

Interactor 2: CRDL2 (Q8VEA6)
Chordin-like protein 2
Gene: Chrdl2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14660436
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001503 - ossification GO:0005615 - extracellular space
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 452 Mm			1 426
+	Mm
		615510 BMP7_MOUSE (31-452): 1.06e-160: 462: 65.72		CRDL2_MOUSE (1-426): 2.8e-92: 286: 100.00
+	Mm
		595651 BMP6_MOUSE (36-452): 7.96e-148: 432: 58.67		CRDL2_MOUSE (1-426): 2.8e-92: 286: 100.00
+	Mm
		597616 BMP2_MOUSE (42-451): 4.19e-108: 327: 29.29		CRDL2_MOUSE (1-426): 2.8e-92: 286: 100.00
+	Mm
		597618 BMP4_MOUSE (40-451): 1.05e-105: 321: 28.07		CRDL2_MOUSE (1-426): 2.8e-92: 286: 100.00
+	Mm
		792933 GDF5_MOUSE (42-451): 7.34e-93: 291: 25.57		CRDL2_MOUSE (1-426): 2.8e-92: 286: 100.00
+	Hs
		439888 INHBA_HUMAN (61-451): 4.28e-89: 279: 18.39		CRDL2_HUMAN (1-425): 3.17e-80: 255: 72.49
+	Dm
		646121 60A_DROME (31-452): 1.96e-127: 378: 33.65		Q9W2H2_DROME (138-315): 7.73e-11: 66.1: 17.58
+	Hs
		351256 TGFB1_HUMAN (40-451): 3.29e-75: 242: 18.96		TENX_HUMAN (1-357): 4e-50: 184: 13.24
+	Rn
		566271 TGFB1_RAT (40-451): 5.77e-82: 259: 19.91		Q71SA3_RAT (28-338): 1.56e-42: 162: 16.62
+	Hs
		358592 BMP2_HUMAN (42-451): 1.04e-106: 323: 29.69		CO2A1_HUMAN (214-321): 1.93e-15: 80.7: 23.15
+	Xl
		1265027 Q91597_XENLA (94-452): 5.68e-100: 306: 28.84		CHRD_XENLA (21-196): 8.41e-21: 97.3: 26.88
+	Hs
		351223 TGFB1_HUMAN (40-451): 3.29e-75: 242: 18.96		TSP1_HUMAN (28-338): 4.15e-41: 158: 16.92
+	Mm
		597617 BMP4_MOUSE (40-451): 1.05e-105: 321: 28.07		BMPER_MOUSE (22-235): 2.18e-10: 64.6: 18.47
+	Dm
		871198 SCW_DROME (31-452): 1.38e-100: 308: 26.78		SOG_DROME (191-347): 1.33e-10: 65.7: 18.44
+	Dm
		429979 DECA_DROME (149-451): 3.17e-88: 282: 31.25		Q9W2H2_DROME (138-315): 7.73e-11: 66.1: 17.58
+	Dm
		429968 DECA_DROME (149-451): 3.17e-88: 282: 31.25		SOG_DROME (191-347): 1.33e-10: 65.7: 18.44
+	Hs
		351208 TGFB1_HUMAN (40-451): 3.29e-75: 242: 18.96		CO2A1_HUMAN (214-321): 1.93e-15: 80.7: 23.15
+	Mm
		380162 TGFB1_MOUSE (40-451): 5.02e-82: 259: 20.62		CO1A1_MOUSE (106-187): 8.32e-09: 59.9: 22.89
+	Hs
		351222 TGFB1_HUMAN (40-451): 3.29e-75: 242: 18.96		LAMB1_HUMAN (32-255): 2.04e-10: 64.9: 12.30
+	Hs
		155756 GDF8_HUMAN (60-451): 1.4e-72: 235: 20.46		LAMB2_HUMAN (79-317): 3.9e-09: 61.1: 10.90