Protein: BTAF1
TATA-binding protein-associated factor MOT1 (TBP-associated factor MOT1) (EC 3.6.4.-) (Modifier of transcription 1)

Gene: BTAF1, MOT1
Organism: Saccharomyces cerevisiae S288C
Interactions: 168
UniProt ID: P32333

Gene Ontology (top 5):
GO:0000228 - nuclear chromosome
GO:0003677 - DNA binding
GO:0004386 - helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

561432

TBP
TATA-box-binding protein

18

6

Small-scale

0.988

High

381939

H4
Histone H4

4

18

Small-scale

0.881

High

419647

H2A2
Histone H2A.2

4

20

High-throughput

0.881

High

734417

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

3

16

Small-scale

0.855

High

734400

STH1
Nuclear protein STH1/NPS1

2

16

Small-scale

0.789

High

381009

H2B1
Histone H2B.1

2

20

High-throughput

0.776

High

381445

H2B2
Histone H2B.2

2

20

High-throughput

0.759

High

734416

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

2

16

Small-scale

0.754

High

734458

H3
Histone H3

2

20

High-throughput

0.737

High

734507

NCB2
Negative cofactor 2 complex subunit beta

4

6

Small-scale

0.672

High

734468

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

3

6

Small-scale

0.656

High

734409

NCBP1
Nuclear cap-binding protein complex subunit 1

1

2

Small-scale

0.647

High

734426

NCB1
Negative cofactor 2 complex subunit alpha

3

5

Small-scale

0.640

High

734447

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

3

4

Small-scale

0.640

High

638788

REB1
DNA-binding protein REB1

2

8

High-throughput

0.621

High

638983

VPS1
Vacuolar protein sorting-associated protein 1

2

5

High-throughput

0.621

High

419381

H2A1
Histone H2A.1

1

20

High-throughput

0.618

High

594248

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

7

High-throughput

0.618

High

734389

BTAF1
TATA-binding protein-associated factor MOT1

1

17

Small-scale

0.618

High

734401

CHD1
Chromo domain-containing protein 1

1

16

Small-scale

0.618

High

734448

INO80
Chromatin-remodeling ATPase INO80

1

16

Small-scale

0.618

High

734452

ASCC3
RQC trigger complex helicase SLH1

1

19

High-throughput

0.618

High

734455

ARP5
Actin-related protein 5

1

18

Small-scale

0.618

High

734459

ARP4
Actin-related protein 4

1

20

Small-scale

0.618

High

734469

RUVB1
RuvB-like protein 1

1

12

Small-scale

0.618

High

734477

ARP9
Actin-like protein ARP9

1

20

Small-scale

0.618

High

734478

HRQ1
ATP-dependent helicase HRQ1

1

20

Small-scale

0.618

High

734485

ULS1
ATP-dependent helicase ULS1

1

17

Small-scale

0.618

High

734487

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

16

Small-scale

0.618

High

734498

ARP8
Actin-like protein ARP8

1

19

Small-scale

0.618

High

734499

DBP10
ATP-dependent RNA helicase DBP10

1

20

High-throughput

0.618

High

734500

ARP7
Actin-related protein 7

1

20

Small-scale

0.618

High

734502

RUVB2
RuvB-like protein 2

1

12

Small-scale

0.618

High

734504

CMR1
DNA damage-binding protein CMR1

1

19

High-throughput

0.618

High

734480

RSC3
Chromatin structure-remodeling complex protein RSC3

2

4

Small-scale

0.611

High

547857

NHP6B
Non-histone chromosomal protein 6B

2

20

High-throughput

0.588

High

597407

EF3A
Elongation factor 3A

2

3

High-throughput

0.588

High

734408

GCN1
eIF-2-alpha kinase activator GCN1

2

4

High-throughput

0.588

High

734441

RFX1
RFX-like DNA-binding protein RFX1

2

8

High-throughput

0.588

High

449442

SPT3
SAGA complex subunit SPT3

2

1

Small-scale

0.584

High

734393

NGG1
SAGA complex subunit NGG1

2

1

Small-scale

0.584

High

734410

SPT7
SAGA complex subunit SPT7

2

20

Small-scale

0.584

High

734422

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

2

11

Small-scale

0.584

High

734434

DSN1
Kinetochore-associated protein DSN1

2

5

High-throughput

0.584

High

734443

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

2

12

Small-scale

0.584

High

734445

SPT20
SAGA complex subunit SPT20

2

1

Small-scale

0.584

High

734461

ADA2
SAGA complex subunit ADA2

2

20

Small-scale

0.584

High

734474

POB3
FACT complex subunit POB3

2

10

Small-scale

0.584

High

734476

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

2

5

Small-scale

0.584

High

734491

HFI1
SAGA complex subunit HFI1

2

1

Small-scale

0.584

High

444452

DED1
ATP-dependent RNA helicase DED1

1

13

High-throughput

0.575

High

734505

H2AZ
Histone H2A.Z

1

20

High-throughput

0.575

High

734407

MSN2
Zinc finger protein MSN2

2

14

Small-scale

0.571

High

734413

SPT10
Protein SPT10

2

5

High-throughput

0.571

High

734429

ATAD2
ATPase histone chaperone YTA7

2

12

High-throughput

0.571

High

734466

GCN5
Histone acetyltransferase GCN5

2

20

Small-scale

0.571

High

734475

RCO1
Transcriptional regulatory protein RCO1

2

20

Small-scale

0.571

High

734484

RSC58
Chromatin structure-remodeling complex protein RSC58

2

3

Small-scale

0.571

High

439284

PDC1
Pyruvate decarboxylase isozyme 1

2

0

High-throughput

0.563

High

734488

NCBP2
Nuclear cap-binding protein subunit 2

1

13

Small-scale

0.561

High

734423

SPT8
SAGA complex subunit SPT8

2

0

Small-scale

0.559

High

734450

SGF73
SAGA complex subunit SGF73

2

0

Small-scale

0.559

High

734506

SUS1
SAGA complex subunit SUS1

2

0

Small-scale

0.559

High

526147

HSP72
Heat shock protein SSA2

2

20

High-throughput

0.552

High

544124

SSB1
Ribosome-associated molecular chaperone SSB1

2

20

High-throughput

0.552

High

416871

CDC25
Cell division control protein 25

1

1

High-throughput

0.541

High

358150

ADH1
Alcohol dehydrogenase 1

2

3

High-throughput

0.537

High

434916

RS3
Small ribosomal subunit protein uS3

1

6

High-throughput

0.536

High

734462

ABF2
ARS-binding factor 2, mitochondrial

1

20

High-throughput

0.536

High

734470

HMO1
High mobility group protein 1

1

20

High-throughput

0.536

High

734395

SPT16
FACT complex subunit SPT16

2

7

Small-scale

0.533

High

734460

RSC4
Chromatin structure-remodeling complex subunit RSC4

2

20

Small-scale

0.521

High

734394

RPN12
26S proteasome regulatory subunit RPN12

1

0

High-throughput

0.493

High

734430

PPAL
Low molecular weight phosphotyrosine protein phosphatase

1

0

High-throughput

0.493

High

427177

RLA0
Large ribosomal subunit protein uL10

1

3

High-throughput

0.489

High

734438

IOC3
ISWI one complex protein 3

1

2

High-throughput

0.489

High

624876

MED15
Mediator of RNA polymerase II transcription subunit 15

1

1

Small-scale

0.479

High

678299

RSC6
Chromatin structure-remodeling complex protein RSC6

1

20

Small-scale

0.479

High

706461

TF2B
Transcription initiation factor IIB

1

6

High-throughput

0.479

High

734392

HIR2
Protein HIR2

1

20

Small-scale

0.479

High

734396

RPD3
Histone deacetylase RPD3

1

20

Small-scale

0.479

High

734397

MED17
Mediator of RNA polymerase II transcription subunit 17

1

2

Small-scale

0.479

High

734403

RSC7
Chromatin structure-remodeling complex subunit RSC7

1

4

Small-scale

0.479

High

734404

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

13

High-throughput

0.479

High

734411

TAF14
Transcription initiation factor TFIID subunit 14

1

4

Small-scale

0.479

High

734419

RSC30
Chromatin structure-remodeling complex protein RSC30

1

4

Small-scale

0.479

High

734420

MED6
Mediator of RNA polymerase II transcription subunit 6

1

2

Small-scale

0.479

High

734431

MED3
Mediator of RNA polymerase II transcription subunit 3

1

1

Small-scale

0.479

High

734439

RSC8
Chromatin structure-remodeling complex protein RSC8

1

20

Small-scale

0.479

High

734446

PHO23
Transcriptional regulatory protein PHO23

1

4

Small-scale

0.479

High

734449

ITC1
Imitation switch two complex protein 1

1

20

Small-scale

0.479

High

734454

APJ1
J domain-containing protein APJ1

1

12

High-throughput

0.479

High

734457

ORC1
Origin recognition complex subunit 1

1

7

High-throughput

0.479

High

734465

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

3

Small-scale

0.479

High

734467

NHP10
Non-histone protein 10

1

20

Small-scale

0.479

High

734471

SIZ1
E3 SUMO-protein ligase SIZ1

1

7

High-throughput

0.479

High

734473

DPB4
DNA polymerase epsilon subunit D

1

6

Small-scale

0.479

High

734479

SFH1
Chromatin structure-remodeling complex subunit SFH1

1

12

Small-scale

0.479

High

734486

ESA1
Histone acetyltransferase ESA1

1

10

Small-scale

0.479

High

734489

CTI6
Histone deacetylase complex subunit CTI6

1

8

Small-scale

0.479

High

734490

TAF10
SAGA complex/transcription factor TFIID complex subunit TAF10

1

2

High-throughput

0.479

High

734493

SCC1
Sister chromatid cohesion protein 1

1

8

High-throughput

0.479

High

734495

SIZ2
E3 SUMO-protein ligase SIZ2

1

6

High-throughput

0.479

High

734509

HTL1
High temperature lethal protein 1

1

3

Small-scale

0.479

High

734497

RPN6
26S proteasome regulatory subunit RPN6

1

1

High-throughput

0.470

High

734402

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

Small-scale

0.460

High

700172

POP5
Ribonuclease P/MRP protein subunit POP5

1

0

High-throughput

0.458

High

726257

DEP1
Transcriptional regulatory protein DEP1

1

0

Small-scale

0.458

High

734390

SFP1
Transcription factor SFP1

1

0

Small-scale

0.458

High

734398

MED18
Mediator of RNA polymerase II transcription subunit 18

1

0

Small-scale

0.458

High

734433

SDS3
Transcriptional regulatory protein SDS3

1

0

Small-scale

0.458

High

734436

STB1
Protein STB1

1

0

Small-scale

0.458

High

734437

EPL1
Enhancer of polycomb-like protein 1

1

0

Small-scale

0.458

High

734444

STB4
Probable transcriptional regulatory protein STB4

1

0

Small-scale

0.458

High

734463

UME1
Transcriptional regulatory protein UME1

1

0

Small-scale

0.458

High

734464

SGF11
SAGA complex subunit SGF11

1

0

Small-scale

0.458

High

734483

RXT3
Transcriptional regulatory protein RXT3

1

0

Small-scale

0.458

High

734494

YP245
Uncharacterized protein YPL245W

1

0

High-throughput

0.458

High

734496

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

Small-scale

0.458

High

734501

EAF3
Chromatin modification-related protein EAF3

1

0

Small-scale

0.458

High

734508

MED11
Mediator of RNA polymerase II transcription subunit 11

1

0

Small-scale

0.458

High

394337

EF1A
Elongation factor 1-alpha

1

4

High-throughput

0.445

High

448148

HAP2
Transcriptional activator HAP2

1

5

High-throughput

0.445

High

453473

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.445

High

486079

TBA1
Tubulin alpha-1 chain

1

8

High-throughput

0.445

High

488931

SWI6
Regulatory protein SWI6

1

12

High-throughput

0.445

High

531651

RL4A
Large ribosomal subunit protein uL4A

1

6

High-throughput

0.445

High

547770

NHP6A
Non-histone chromosomal protein 6A

1

20

High-throughput

0.445

High

548758

MCM1
Pheromone receptor transcription factor

1

9

High-throughput

0.445

High

570791

ABF1
ARS-binding factor 1

1

2

High-throughput

0.445

High

592083

VATB
V-type proton ATPase subunit B

1

6

High-throughput

0.445

High

645595

AFT1
Iron-regulated transcriptional activator AFT1

1

3

High-throughput

0.445

High

649930

SIN3
Transcriptional regulatory protein SIN3

1

17

High-throughput

0.445

High

671505

SWI4
Regulatory protein SWI4

1

12

High-throughput

0.445

High

675799

MAS5
Mitochondrial protein import protein MAS5

1

12

High-throughput

0.445

High

684654

RL5
Large ribosomal subunit protein uL18

1

5

High-throughput

0.445

High

726827

HS104
Heat shock protein 104

1

6

High-throughput

0.445

High

734391

ASF1
Histone chaperone ASF1

1

12

High-throughput

0.445

High

734399

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

734406

IXR1
Intrastrand cross-link recognition protein

1

20

High-throughput

0.445

High

734414

LHS1
Heat shock protein 70 homolog LHS1

1

20

High-throughput

0.445

High

734415

SET3
SET domain-containing protein 3

1

20

High-throughput

0.445

High

734421

SSZ1
Ribosome-associated complex subunit SSZ1

1

16

High-throughput

0.445

High

734425

HSP7E
Heat shock protein SSC3, mitochondrial

1

20

High-throughput

0.445

High

734427

SSB2
Ribosome-associated molecular chaperone SSB2

1

20

High-throughput

0.445

High

734428

RT106
Histone chaperone RTT106

1

4

High-throughput

0.445

High

734432

DLS1
Protein DLS1

1

1

High-throughput

0.445

High

734442

RL4B
Large ribosomal subunit protein uL4B

1

6

High-throughput

0.445

High

734456

CRZ1
Transcriptional regulator CRZ1

1

7

High-throughput

0.445

High

734482

BRE1
E3 ubiquitin-protein ligase BRE1

1

18

High-throughput

0.445

High

734503

CAF1A
Chromatin assembly factor 1 subunit A

1

16

High-throughput

0.445

High

512038

RS4A
Small ribosomal subunit protein eS4A

1

2

High-throughput

0.437

High

734405

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

734418

LDB7
Chromatin structure-remodeling complex protein RSC14

1

3

Small-scale

0.437

High

734424

TEM1
Protein TEM1

1

5

High-throughput

0.437

High

734451

YG3A
Uncharacterized protein YGR130C

1

20

Small-scale

0.437

High

734472

IOC4
ISWI one complex protein 4

1

3

Small-scale

0.437

High

734492

IOC2
ISWI one complex protein 2

1

3

Small-scale

0.437

High

450545

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.426

High

734481

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

0

High-throughput

0.426

High

688845

RS5
Small ribosomal subunit protein uS7

1

2

High-throughput

0.407

High

734039

EF2
Elongation factor 2

1

6

High-throughput

0.407

High

734435

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.407

High

734453

PFD4
Prefoldin subunit 4

1

1

High-throughput

0.407

High

688784

RFA3
Replication factor A protein 3

1

0

Small-scale

0.249

Low

734412

CSG2
Mannosyl phosphorylinositol ceramide synthase regulatory protein CSG2

1

0

High-throughput

0.249

Low

734440

MHP1
MAP-homologous protein 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025