HitPredict

Interactor 1: NR2C2 (P49116)
Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TAK1) (Orphan nuclear receptor TR4) (Testicular receptor 4)
Gene: NR2C2

Interactor 2: CBX3 (Q13185)
Chromobox protein homolog 3 (HECH) (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein)
Gene: CBX3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30463901, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 596 Hs			1 183
+	Hs
		800315 NR2C2_HUMAN (1-596): 0: 527: 100.00		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		823885 NR2C2_HUMAN (1-596): 0: 527: 100.00		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		824545 NR2C2_HUMAN (1-596): 0: 527: 100.00		CDYL_HUMAN (16-165): 6.53e-34: 127: 25.16
+	Dm
		1096258 HR78_DROME (82-580): 1.38e-77: 259: 25.39		Q95SE0_DROME (29-175): 3.4e-52: 168: 56.95
+	Dm
		1096380 HR78_DROME (82-580): 1.38e-77: 259: 25.39		Q9W396_DROME (29-175): 4.55e-52: 168: 56.95
+	Hs
		490090 COT1_HUMAN (47-193): 9.02e-48: 174: 41.45		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		487919 RARA_HUMAN (66-191): 1.29e-27: 118: 44.53		CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89
+	Hs
		490058 NR2F6_HUMAN (386-576): 3.59e-24: 107: 36.13		CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33
+	Hs
		203617 RARA_HUMAN (66-191): 1.29e-27: 118: 44.53		SUV91_HUMAN (3-179): 4.73e-40: 141: 16.20
+	Hs
		203691 Q15156_HUMAN (92-191): 6.42e-26: 115: 50.98		SUV91_HUMAN (3-179): 4.73e-40: 141: 16.20