Interactor 1: ITB1 (P49134)
Integrin beta-1 (Beta oligodendroglia) (Beta OL) (Fibronectin receptor subunit beta) (VLA-4 subunit beta) (CD antigen CD29)
Gene: Itgb1

Interactor 2: ADA17 (Q9Z1K9)
Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b)
Gene: Adam17

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 22413019
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains Disintegrin~EGF_2
Common GO terms GO:0005178 - integrin binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0009410 - response to xenobiotic stimulus
and 8 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 799
Rn

1 827
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024