HitPredict

Interactor 1: SOX2 (P48432)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: RUVB1 (P60122)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (DNA helicase p50) (Pontin 52) (TIP49a)
Gene: Ruvbl1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31077711
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 319 Mm			1 456
+	Mm
		888064 Q60I23_MOUSE (1-319): 1.52e-65: 210: 98.43		RUVB1_MOUSE (1-456): 0: 716: 100.00
+	Hs
		818624 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		RUVB1_HUMAN (1-456): 0: 715: 99.78
+	Hs
		1301007 CIC_HUMAN (10-274): 4.32e-43: 160: 23.83		RUVB1_HUMAN (1-456): 0: 715: 99.78
+	Mm
		1142023 Q60I23_MOUSE (1-319): 1.52e-65: 210: 98.43		RUVB2_MOUSE (2-455): 0: 649: 42.76
+	Hs
		818621 SOX2_HUMAN (1-319): 2.01e-64: 207: 94.67		RUVB2_HUMAN (2-455): 0: 649: 42.76
+	Mm
		818777 SOX2_MOUSE (1-319): 3.85e-64: 207: 100.00		RUVB2_MOUSE (2-455): 0: 649: 42.76
+	Hs
		1301006 CIC_HUMAN (10-274): 4.32e-43: 160: 23.83		RUVB2_HUMAN (2-455): 0: 649: 42.76