Protein: SHY1
Cytochrome oxidase assembly protein SHY1 (SURF1 homolog of Yeast) (SURF1-like protein)

Gene: SHY1
Organism: Saccharomyces cerevisiae S288C
Interactions: 64
UniProt ID: P53266

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005777 - peroxisome
GO:0016020 - membrane
GO:0033617 - mitochondrial cytochrome c oxidase assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

734567

MSS51
Protein MSS51, mitochondrial

6

0

Small-scale

0.697

High

453185

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

4

1

Small-scale

0.691

High

824678

COA1
Cytochrome c oxidase assembly factor 1

4

0

Small-scale

0.667

High

811517

COX14
Cytochrome c oxidase assembly protein COX14

4

0

Small-scale

0.661

High

919091

COA3
Cytochrome c oxidase assembly factor 3, mitochondrial

4

0

Small-scale

0.657

High

360342

COX1
Cytochrome c oxidase subunit 1

3

0

Small-scale

0.628

High

360802

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

3

0

Small-scale

0.628

High

360897

COX6
Cytochrome c oxidase subunit 6, mitochondrial

2

1

Small-scale

0.611

High

399866

COX4
Cytochrome c oxidase subunit 4, mitochondrial

2

1

Small-scale

0.611

High

818407

COX15
Heme A synthase COX15

2

1

Small-scale

0.611

High

360676

COX2
Cytochrome c oxidase subunit 2

2

1

Small-scale

0.584

High

781427

MIC60
MICOS complex subunit MIC60

2

0

High-throughput

0.559

High

453297

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

1

Small-scale

0.536

High

450459

CY1
Cytochrome c1, heme protein, mitochondrial

1

0

Small-scale

0.513

High

357891

CYB
Cytochrome b

1

1

Small-scale

0.479

High

397568

MBI4
Intron-encoded RNA maturase bI4

1

1

Small-scale

0.479

High

635979

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

1

Small-scale

0.479

High

723192

ATP7
ATP synthase subunit d, mitochondrial

1

1

Small-scale

0.479

High

815702

OXA1
Mitochondrial inner membrane protein OXA1

1

1

High-throughput

0.479

High

64265

YP010
UPF0495 protein YPR010C-A

1

0

Small-scale

0.458

High

357777

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

Small-scale

0.458

High

368468

TPIS
Triosephosphate isomerase

1

0

Small-scale

0.458

High

417153

VDAC1
Non-selective voltage-gated ion channel 1

1

0

Small-scale

0.458

High

465350

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

Small-scale

0.458

High

484784

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

Small-scale

0.458

High

579797

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

736284

RM41
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.458

High

746897

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

748610

SRPR
Signal recognition particle receptor subunit alpha homolog

1

0

Small-scale

0.458

High

784116

RM15
Large ribosomal subunit protein mL57

1

0

High-throughput

0.458

High

797637

MBA1
Inner membrane mitoribosome receptor MBA1, mitochondrial

1

0

High-throughput

0.458

High

798482

MIC12
MICOS complex subunit MIC12

1

0

High-throughput

0.458

High

813422

PO152
Nucleoporin POM152

1

0

Small-scale

0.458

High

820351

YNU8
Uncharacterized protein YNL208W

1

0

Small-scale

0.458

High

878362

COQ5
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial

1

0

Small-scale

0.458

High

916850

ZIP2
Protein ZIP2

1

0

Small-scale

0.458

High

919092

COA2
Cytochrome c oxidase assembly factor 2

1

0

Small-scale

0.458

High

415113

ADT1
ADP,ATP carrier protein 1

1

1

Small-scale

0.445

High

676201

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

511088

YRF13
Y' element ATP-dependent helicase protein 1 copy 3

1

6

Small-scale

0.437

High

511093

YE076
Putative uncharacterized protein YEL076C-A

1

6

Small-scale

0.437

High

511104

YRF15
Y' element ATP-dependent helicase protein 1 copy 5

1

7

Small-scale

0.437

High

816075

YEI6
Uncharacterized protein YEL076C

1

6

Small-scale

0.437

High

818680

YRF12
Y' element ATP-dependent helicase protein 1 copy 2

1

7

Small-scale

0.437

High

824608

YIR7
Y' element ATP-dependent helicase YIL177C

1

6

Small-scale

0.437

High

919083

YRF16
Y' element ATP-dependent helicase protein 1 copy 6

1

6

Small-scale

0.437

High

919086

NU116
Nucleoporin NUP116/NSP116

1

1

Small-scale

0.437

High

819356

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

863670

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

886169

NUP42
Nucleoporin NUP42

1

1

Small-scale

0.407

High

639867

SIR1
Regulatory protein SIR1

1

0

Small-scale

0.249

Low

756647

NIC96
Nucleoporin NIC96

1

0

Small-scale

0.249

Low

803154

ECM29
Proteasome component ECM29

1

0

Small-scale

0.249

Low

817809

NU157
Nucleoporin NUP157

1

0

Small-scale

0.249

Low

823490

NUP82
Nucleoporin NUP82

1

0

Small-scale

0.249

Low

825706

SPO22
Sporulation-specific protein 22

1

0

Small-scale

0.249

Low

919082

SCW4
Probable family 17 glucosidase SCW4

1

0

Small-scale

0.249

Low

919084

ASI3
Probable ERAD-associated E3 ubiquitin-protein ligase ASI1

1

0

Small-scale

0.249

Low

919087

WDR59
Maintenance of telomere capping protein 5

1

0

Small-scale

0.249

Low

919088

CTR3
Copper transport protein CTR3

1

0

Small-scale

0.249

Low

919089

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

919090

NTO1
NuA3 HAT complex component NTO1

1

0

Small-scale

0.249

Low

919085

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

742054

HSP7F
Heat shock protein homolog SSE1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025