HitPredict

Interactor 1: NRAM2 (P49281)
Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent cation transporter 1) (Divalent metal transporter 1) (DMT-1) (Solute carrier family 11 member 2)
Gene: SLC11A2

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0016020 - membrane GO:0045177 - apical part of cell
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 568 Hs			1 191
+	Hs
		825667 NRAM2_HUMAN (1-568): 0: 712: 100.00		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		825655 NRAM2_HUMAN (1-568): 0: 712: 100.00		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		825656 NRAM2_HUMAN (1-568): 0: 712: 100.00		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		825653 NRAM2_HUMAN (1-568): 0: 712: 100.00		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		545262 NRAM2_HUMAN (1-568): 0: 712: 100.00		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		436204 NRAM2_HUMAN (1-568): 0: 712: 100.00		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		825651 NRAM2_HUMAN (1-568): 0: 712: 100.00		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32