HitPredict

Interactor 1: ARRB1 (P49407)
Beta-arrestin-1 (Arrestin beta-1) (Non-visual arrestin-2)
Gene: ARRB1

Interactor 2: M3K14 (Q99558)
Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (HsNIK) (Serine/threonine-protein kinase NIK)
Gene: MAP3K14

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15173580
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 418 Hs			1 947
+	Hs
		686042 ARRB2_HUMAN (1-407): 0: 626: 76.15		M3K14_HUMAN (1-947): 0: 799: 100.00
+	Hs
		681739 ARRB1_HUMAN (1-418): 0: 716: 100.00		AKT1_HUMAN (286-713): 3.76e-131: 405: 19.33
+	Mm
		682118 ARRB1_MOUSE (1-418): 0: 703: 98.57		AKT1_MOUSE (286-713): 1.66e-131: 406: 20.22
+	Hs
		682136 ARRB2_HUMAN (1-407): 0: 626: 76.15		AKT2_HUMAN (286-701): 1.96e-133: 411: 20.32
+	Hs
		681683 ARRB2_HUMAN (1-407): 0: 626: 76.15		AKT1_HUMAN (286-713): 3.76e-131: 405: 19.33
+	Mm
		682122 ARRB2_MOUSE (1-407): 0: 615: 75.00		AKT1_MOUSE (286-713): 1.66e-131: 406: 20.22
+	Hs
		827185 ARRB1_HUMAN (1-418): 0: 716: 100.00		M3K1_HUMAN (370-643): 2.05e-24: 112: 30.52
+	Hs
		685929 ARRB2_HUMAN (1-407): 0: 626: 76.15		M3K1_HUMAN (370-643): 2.05e-24: 112: 30.52