HitPredict

Interactor 1: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA

Interactor 2: PB1 (Q86U86)
Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)
Gene: PBRM1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 140 Hs			1 1689
+	Hs
		934930 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		PB1_HUMAN (1-1689): 0: 1223: 100.00
+	Hs
		1086201 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		PB1_HUMAN (1-1689): 0: 1223: 100.00
+	Hs
		641169 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20
+	Hs
		641190 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20
+	Hs
		641229 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20
+	Hs
		828394 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		BRWD1_HUMAN (2-959): 3.8e-58: 224: 12.26
+	Hs
		600099 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		TAF1_HUMAN (457-963): 1.08e-57: 223: 16.79
+	Hs
		600123 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		TAF1_HUMAN (457-963): 1.08e-57: 223: 16.79
+	Hs
		600156 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		TAF1_HUMAN (457-963): 1.08e-57: 223: 16.79
+	Hs
		828320 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50
+	Hs
		935038 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50
+	Hs
		828234 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		934782 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		631374 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		631395 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		935276 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		ASH1L_HUMAN (535-651): 1.26e-11: 72.4: 29.92
+	Hs
		828175 CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00		SMCA2_HUMAN (794-881): 2.15e-09: 64.9: 26.09
+	Hs
		846921 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		SMCA4_HUMAN (764-881): 7.55e-11: 69.5: 23.58
+	Hs
		846989 H31T_HUMAN (5-134): 1.01e-51: 162: 48.09		SMCA4_HUMAN (764-881): 7.55e-11: 69.5: 23.58
+	Hs
		846743 H31_HUMAN (5-134): 1.29e-52: 164: 48.86		SMCA2_HUMAN (794-881): 2.15e-09: 64.9: 26.09