Protein: SYA
Alanine--tRNA ligase, mitochondrial (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)

Gene: SYA, ALA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 61
UniProt ID: P40825

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0002161 - aminoacyl-tRNA deacylase activity
GO:0004813 - alanine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

828269

SYA
Alanine--tRNA ligase, mitochondrial

1

12

High-throughput

0.665

High

392875

HSP82
ATP-dependent molecular chaperone HSP82

3

8

Small-scale

0.633

High

828270

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

579559

HSC82
ATP-dependent molecular chaperone HSC82

2

8

High-throughput

0.571

High

727098

HS104
Heat shock protein 104

2

5

High-throughput

0.571

High

526914

HSP72
Heat shock protein SSA2

2

7

High-throughput

0.552

High

818981

SSB2
Ribosome-associated molecular chaperone SSB2

2

7

High-throughput

0.552

High

545198

SSB1
Ribosome-associated molecular chaperone SSB1

1

7

High-throughput

0.536

High

628073

FKBP
FK506-binding protein 1

1

9

High-throughput

0.536

High

734312

DBF20
Serine/threonine-protein kinase DBF20

1

1

High-throughput

0.536

High

828279

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

1

1

High-throughput

0.515

High

738660

EI2BB
Translation initiation factor eIF2B subunit beta

1

0

High-throughput

0.513

High

642402

MCK1
Protein kinase MCK1

1

3

High-throughput

0.501

High

740582

IME2
Meiosis induction protein kinase IME2/SME1

1

2

High-throughput

0.501

High

758304

HSL1
Probable serine/threonine-protein kinase HSL1

1

2

High-throughput

0.501

High

778940

KKQ8
Probable serine/threonine-protein kinase KKQ8

1

4

High-throughput

0.501

High

800713

RCK1
Serine/threonine-protein kinase RCK1

1

1

High-throughput

0.501

High

801848

KSP1
Serine/threonine-protein kinase KSP1

1

1

High-throughput

0.501

High

808639

AURK
Aurora kinase

1

2

High-throughput

0.501

High

815464

RSP5
E3 ubiquitin-protein ligase RSP5

1

5

High-throughput

0.501

High

822249

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

1

High-throughput

0.501

High

828272

IKS1
Probable serine/threonine-protein kinase IKS1

1

1

High-throughput

0.501

High

828274

ATPJ
ATP synthase subunit e, mitochondrial

1

0

High-throughput

0.493

High

625019

PRP6
Pre-mRNA-splicing factor 6

1

2

High-throughput

0.489

High

666191

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

1

0

High-throughput

0.480

High

828278

ISR1
Serine/threonine-protein kinase ISR1

1

0

High-throughput

0.480

High

828280

PSK2
Serine/threonine-protein kinase PSK2

1

0

High-throughput

0.480

High

435149

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

454738

KAPR
cAMP-dependent protein kinase regulatory subunit

1

1

Small-scale

0.479

High

707342

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

709815

BMH1
Protein BMH1

1

1

High-throughput

0.479

High

750693

PRS6A
26S proteasome regulatory subunit 6A

1

3

High-throughput

0.479

High

795401

ATG8
Autophagy-related protein 8

1

2

High-throughput

0.479

High

803580

RPN1
26S proteasome regulatory subunit RPN1

1

2

High-throughput

0.479

High

812054

DHH1
ATP-dependent RNA helicase DHH1

1

3

High-throughput

0.479

High

828273

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

828276

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

828285

DBP10
ATP-dependent RNA helicase DBP10

1

4

High-throughput

0.479

High

828286

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

828275

ESP1
Separin

1

0

High-throughput

0.458

High

828271

CTK2
CTD kinase subunit beta

1

1

High-throughput

0.457

High

828281

ESA1
Histone acetyltransferase ESA1

1

2

Small-scale

0.457

High

376192

RAS1
Ras-like protein 1

1

1

High-throughput

0.445

High

524219

HSP71
Heat shock protein SSA1

1

7

High-throughput

0.445

High

741754

HSP7F
Heat shock protein homolog SSE1

1

12

High-throughput

0.445

High

742869

HSP79
Heat shock protein homolog SSE2

1

12

High-throughput

0.445

High

752364

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.445

High

828277

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

13

High-throughput

0.445

High

441958

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.437

High

503091

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

670813

SIS1
Protein SIS1

1

6

High-throughput

0.437

High

792833

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.437

High

795041

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

806738

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.437

High

828282

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

828283

RRP6
Exosome complex exonuclease RRP6

1

3

High-throughput

0.437

High

394644

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

590648

HSP26
Heat shock protein 26

1

0

High-throughput

0.426

High

828284

JID1
J domain-containing protein 1

1

0

High-throughput

0.426

High

748181

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025