HitPredict

Interactor 1: CENPF (P49454)
Centromere protein F (CENP-F) (AH antigen) (Kinetochore protein CENPF) (Mitosin)
Gene: CENPF

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	35384245, 14968112
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3114 Hs			1 1620
+	Hs
		725069 MYH9_HUMAN (2390-3109): 2.8e-24: 115: 11.50		ALK_HUMAN (1-1620): 0: 1883: 100.00
+	Hs
		666578 DYST_HUMAN (1102-3090): 9.18e-21: 103: 9.74		LTK_HUMAN (606-1458): 6.35e-175: 550: 53.24
+	Hs
		666598 GOGB1_HUMAN (2288-3084): 7.81e-16: 87.4: 11.29		LTK_HUMAN (606-1458): 6.35e-175: 550: 53.24
+	Hs
		666610 GRDN_HUMAN (1949-2897): 1.21e-09: 66.6: 21.17		LTK_HUMAN (606-1458): 6.35e-175: 550: 53.24
+	Hs
		665375 MYH9_HUMAN (2390-3109): 2.8e-24: 115: 11.50		EPHA3_HUMAN (943-1427): 7.27e-120: 404: 25.87
+	Hs
		601499 DYST_HUMAN (1102-3090): 9.18e-21: 103: 9.74		FGFR2_HUMAN (952-1433): 9.52e-123: 407: 25.24
+	Hs
		665392 DYST_HUMAN (1102-3090): 9.18e-21: 103: 9.74		EPHA3_HUMAN (943-1427): 7.27e-120: 404: 25.87
+	Hs
		601523 GRDN_HUMAN (1949-2897): 1.21e-09: 66.6: 21.17		FGFR2_HUMAN (952-1433): 9.52e-123: 407: 25.24
+	Hs
		609293 EEA1_HUMAN (1949-2674): 3.99e-11: 71.6: 21.32		FGFR3_HUMAN (952-1449): 6.42e-121: 401: 26.31
+	Hs
		508036 GRDN_HUMAN (1949-2897): 1.21e-09: 66.6: 21.17		FGFR1_HUMAN (952-1454): 2.04e-118: 395: 26.06
+	Hs
		411404 GRDN_HUMAN (1949-2897): 1.21e-09: 66.6: 21.17		INSR_HUMAN (973-1436): 1.01e-112: 392: 34.25
+	Hs
		435647 EEA1_HUMAN (1949-2674): 3.99e-11: 71.6: 21.32		IGF1R_HUMAN (1037-1385): 8.86e-111: 386: 39.77
+	Hs
		384384 MYH9_HUMAN (2390-3109): 2.8e-24: 115: 11.50		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		974084 DYST_HUMAN (1102-3090): 9.18e-21: 103: 9.74		NTRK2_HUMAN (1093-1375): 7.35e-64: 236: 41.44
+	Hs
		384681 DYST_HUMAN (1102-3090): 9.18e-21: 103: 9.74		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		1083852 GRDN_HUMAN (1949-2897): 1.21e-09: 66.6: 21.17		NTRK2_HUMAN (1093-1375): 7.35e-64: 236: 41.44
+	Hs
		384210 DESP_HUMAN (282-945): 7.09e-11: 70.9: 19.30		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		385802 MRCKB_HUMAN (2279-2818): 8.77e-11: 70.5: 21.73		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		384941 GRDN_HUMAN (1949-2897): 1.21e-09: 66.6: 21.17		NTRK1_HUMAN (1111-1392): 5.05e-62: 230: 42.07
+	Hs
		426943 DESP_HUMAN (282-945): 7.09e-11: 70.9: 19.30		FES_HUMAN (1114-1384): 4.5e-59: 222: 42.80