HitPredict

Interactor 1: CTCF (P49711)
Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog)
Gene: CTCF

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29845934, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 727 Hs			1 582
+	Hs
		977961 ZNF92_HUMAN (341-727): 4.72e-152: 456: 18.73		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		830948 CTCF_HUMAN (1-727): 0: 637: 100.00		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		516412 CTCF_HUMAN (1-727): 0: 637: 100.00		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		831047 CTCF_HUMAN (1-727): 0: 637: 100.00		MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42
+	Hs
		830984 CTCF_HUMAN (1-727): 0: 637: 100.00		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		1116569 ZNF71_HUMAN (176-402): 4.24e-58: 206: 24.67		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		565099 ZNF7_HUMAN (408-631): 5.28e-65: 230: 25.45		MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42
+	Hs
		1343991 ZNF71_HUMAN (176-402): 4.24e-58: 206: 24.67		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84