Interactor 1: C0H5Y5 (C0H5Y5)
CASP8 and FADD-like apoptosis regulator
Gene: Cflar

Interactor 2: TNFA (P16599)
Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]
Gene: Tnf

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 17623297
Identification Methods pull down
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001666 - response to hypoxia
GO:0002020 - protease binding
GO:0009617 - response to bacterium
GO:0043066 - negative regulation of apoptotic process
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
and 2 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 480
Rn

1 235
+ Hs
+ Mm
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+ Hs
+ Rn
+ Hs
+ Rn
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+ Hs

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Last updated: 15 Jul 2024