Protein: SUR2
Sphingolipid C4-hydroxylase SUR2 (EC 1.-.-.-) (Syringomycin response protein 2)

Gene: SUR2
Organism: Saccharomyces cerevisiae S288C
Interactions: 57
UniProt ID: P38992

Gene Ontology (top 5):
GO:0005506 - iron ion binding
GO:0005789 - endoplasmic reticulum membrane
GO:0006665 - sphingolipid metabolic process
GO:0030148 - sphingolipid biosynthetic process
GO:0042284 - sphingolipid delta-4 desaturase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

796926

PHO88
SRP-independent targeting protein 3

3

2

High-throughput

0.669

High

470069

PSS
CDP-diacylglycerol--serine O-phosphatidyltransferase

1

1

High-throughput

0.541

High

528587

CP51
Lanosterol 14-alpha demethylase CYP51

1

3

High-throughput

0.541

High

672805

ELO2
Fatty acid elongase 2

1

6

High-throughput

0.541

High

745335

EMP24
Endosomal protein P24B

1

3

High-throughput

0.541

High

776361

YET1
Endoplasmic reticulum transmembrane protein 1

1

1

High-throughput

0.541

High

780448

SRPB
Signal recognition particle receptor subunit beta

1

2

High-throughput

0.541

High

797386

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

1

2

High-throughput

0.541

High

805879

YHU0
UPF0641 membrane protein YHR140W

1

1

High-throughput

0.541

High

808677

ELO1
Fatty acid elongase 1

1

6

High-throughput

0.541

High

808680

ELO3
Fatty acid elongase 3

1

6

High-throughput

0.541

High

808681

SNL1
HSP70 co-chaperone SNL1

1

1

High-throughput

0.541

High

808684

GPI2
Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit

1

1

High-throughput

0.541

High

808685

SPC1
Signal peptidase complex subunit 1

1

1

High-throughput

0.541

High

808692

TMEDA
Endoplasmic reticulum vesicle protein 25

1

6

High-throughput

0.541

High

808694

SHR3
Secretory component protein SHR3

1

1

High-throughput

0.541

High

808696

GSF2
Glucose-signaling factor 2

1

2

High-throughput

0.541

High

808697

ERP1
Protein ERP1

1

6

High-throughput

0.541

High

808698

ORM2
Protein ORM2

1

2

High-throughput

0.541

High

808702

PFA4
Palmitoyltransferase PFA4

1

1

High-throughput

0.541

High

808703

ERP4
Protein ERP4

1

6

High-throughput

0.541

High

754621

OSTB
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

1

0

High-throughput

0.518

High

805921

CHS7
Chitin synthase export chaperone

1

0

High-throughput

0.518

High

808688

GPI8
GPI-anchor transamidase

1

0

High-throughput

0.518

High

808695

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

1

0

High-throughput

0.518

High

544874

SSB1
Ribosome-associated molecular chaperone SSB1

2

4

High-throughput

0.504

High

687052

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

2

High-throughput

0.494

High

808683

PHO86
Inorganic phosphate transporter PHO86

1

1

High-throughput

0.494

High

808691

TNA1
High-affinity nicotinic acid transporter

1

1

High-throughput

0.494

High

808699

TPO1
Polyamine transporter 1

1

3

High-throughput

0.494

High

808700

YP264
Probable transport protein YPL264C

1

1

High-throughput

0.494

High

808701

SAM3
S-adenosylmethionine permease SAM3

1

3

High-throughput

0.494

High

808704

ENV10
SRP-independent targeting protein 2

1

2

High-throughput

0.479

High

726084

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

0

High-throughput

0.458

High

579389

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.437

High

386708

TBB
Tubulin beta chain

1

1

High-throughput

0.407

High

392729

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.407

High

394560

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.407

High

427279

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.407

High

486176

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.407

High

523948

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.407

High

531741

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.407

High

592251

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

626737

HSP60
Heat shock protein 60, mitochondrial

1

1

High-throughput

0.407

High

808678

HSP7E
Heat shock protein SSC3, mitochondrial

1

2

High-throughput

0.407

High

808679

PFD2
Prefoldin subunit 2

1

1

High-throughput

0.407

High

808682

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.407

High

808687

PFD3
Prefoldin subunit 3

1

1

High-throughput

0.407

High

780600

CAB3
Coenzyme A biosynthesis protein 3

1

0

High-throughput

0.282

High

798710

BSD2
Metal homeostatis protein BSD2

1

0

High-throughput

0.282

High

808690

VSB1
Vacuolar basic amino acid transporter VSB1

1

0

High-throughput

0.282

High

808693

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

808686

YJZ3
Putative uncharacterized protein YJR023C

1

0

High-throughput

0.238

Low

808689

THG1
tRNA(His) guanylyltransferase

1

0

High-throughput

0.238

Low

684725

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.232

Low

688887

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.232

Low

747362

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025