HitPredict - High confidence protein-protein interactions

Interactor 1: CEBPA (P49715)
CCAAT/enhancer-binding protein alpha (C/EBP alpha)
Gene: CEBPA

Interactor 2: ATF5 (Q9Y2D1)
Cyclic AMP-dependent transcription factor ATF-5 (cAMP-dependent transcription factor ATF-5) (Activating transcription factor 5) (Transcription factor ATFx)
Gene: ATF5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	23661758, 20102225
Identification Methods	fluorescent resonance energy transfer, peptide array
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	bZIP_1~bZIP_2
Common GO terms	GO:0000785 - chromatin GO:0000976 - transcription cis-regulatory region binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0003700 - DNA-binding transcription factor activity and 10 others more... GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II GO:0008285 - negative regulation of cell population proliferation GO:0019900 - kinase binding GO:0045444 - fat cell differentiation GO:0045892 - negative regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0090575 - RNA polymerase II transcription regulator complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1	358
Hs

1	282

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Last updated: 15 Jul 2024