HitPredict

Interactor 1: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Interactor 2: TONSL (Q96HA7)
Tonsoku-like protein (Inhibitor of kappa B-related protein) (I-kappa-B-related protein) (IkappaBR) (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2)
Gene: TONSL

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	33961781, 21055985, 21113133, 21055984
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0042393 - histone binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 904 Hs			1 1378
+	Hs
		708498 MCM4_HUMAN (2-885): 0: 847: 28.42		TONSL_HUMAN (1-1378): 0: 641: 100.00
+	Hs
		708731 MCM5_HUMAN (169-902): 0: 768: 29.43		TONSL_HUMAN (1-1378): 0: 641: 100.00
+	Hs
		627329 MCM3_HUMAN (186-897): 0: 725: 29.20		TONSL_HUMAN (1-1378): 0: 641: 100.00
+	Hs
		1055611 MCM6_HUMAN (186-817): 0: 710: 31.18		TONSL_HUMAN (1-1378): 0: 641: 100.00
+	Hs
		709010 MCM7_HUMAN (188-886): 0: 707: 27.35		TONSL_HUMAN (1-1378): 0: 641: 100.00
+	Hs
		832413 MCM2_HUMAN (1-904): 0: 1078: 100.00		ANK3_HUMAN (120-617): 7.94e-49: 194: 16.63
+	Hs
		527967 MCM2_HUMAN (1-904): 0: 1078: 100.00		RINI_HUMAN (1008-1220): 6.76e-22: 102: 17.76
+	Hs
		708430 MCM4_HUMAN (2-885): 0: 847: 28.42		ANK3_HUMAN (120-617): 7.94e-49: 194: 16.63
+	Hs
		1021402 MCM6_HUMAN (186-817): 0: 710: 31.18		ANK3_HUMAN (120-617): 7.94e-49: 194: 16.63
+	Hs
		1055613 MCM6_HUMAN (186-817): 0: 710: 31.18		BARD1_HUMAN (523-674): 2.95e-40: 163: 36.18