Interactor 1: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Interactor 2: CDT1 (Q9H211)
DNA replication factor Cdt1 (Double parked homolog) (DUP)
Gene: CDT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 21930785, 34599168
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CDT1_C~MCM, CDT1_C~MCM_lid, CDT1_C~MCM_OB
Common GO terms GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0030174 - regulation of DNA-templated DNA replication initiation
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 904
Hs

1 546
+ Mm
+ Hs
+ Hs
+ Mm

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Last updated: 15 Jul 2024