Interactor 1: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2
Interactor 2: ASF1A (Q9Y294)
Histone chaperone ASF1A (Anti-silencing function protein 1 homolog A) (hAsf1) (hAsf1a) (CCG1-interacting factor A) (CIA) (hCIA)
Gene: ASF1A
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.974 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25963833, 32296183, 24981860, 33961781, 28514442, 23602572, 22407294, 26167883, unassigned1304 |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation, tandem affinity purification, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ASF1_hist_chap~MCM2_N |
| Common GO terms | GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0042393 - histone binding |
| Homologous interactions | 11 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
