HitPredict

Interactor 1: ACSL1 (P41216)
Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Phytanate--CoA ligase) (EC 6.2.1.24)
Gene: ACSL1

Interactor 2: ACSL1 (P41216)
Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Phytanate--CoA ligase) (EC 6.2.1.24)
Gene: ACSL1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 29199018, 29222160, 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AMP-binding~AMP-binding
Common GO terms GO:0000038 - very long-chain fatty acid metabolic process
GO:0001676 - long-chain fatty acid metabolic process
GO:0004467 - long-chain fatty acid-CoA ligase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
and 21 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 699
Mm

1 699
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025