HitPredict

Interactor 1: CSK (P41240)
Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)
Gene: CSK

Interactor 2: CAV1 (Q03135)
Caveolin-1
Gene: CAV1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.661

Property	Details
Experiments	24632723, 11805080, 16678999
Identification Methods	affinity chromatography technology, pull down, two hybrid, coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0031295 - T cell costimulation GO:0071375 - cellular response to peptide hormone stimulus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 450 Hs			1 178
+	Mm
		834247 CSK_MOUSE (1-450): 0: 542: 99.11		CAV1_MOUSE (1-178): 4.65e-108: 308: 94.94
+	Hs
		362250 ABL1_HUMAN (7-447): 4.27e-164: 493: 38.00		CAV1_HUMAN (1-178): 2.83e-109: 310: 100.00
+	Hs
		557242 SRC_HUMAN (12-442): 4.98e-171: 492: 39.33		CAV1_HUMAN (1-178): 2.83e-109: 310: 100.00
+	Hs
		463065 YES_HUMAN (12-442): 5.09e-170: 490: 37.30		CAV1_HUMAN (1-178): 2.83e-109: 310: 100.00
+	Hs
		840949 ABL2_HUMAN (4-443): 4.34e-160: 484: 39.33		CAV1_HUMAN (1-178): 2.83e-109: 310: 100.00
+	Hs
		463468 LYN_HUMAN (4-445): 1.19e-159: 462: 37.12		CAV1_HUMAN (1-178): 2.83e-109: 310: 100.00
+	Mm
		431333 SRC_MOUSE (12-442): 1.18e-169: 488: 39.55		CAV3_MOUSE (35-177): 1.82e-76: 227: 65.73
+	Hs
		557183 SRC_HUMAN (12-442): 4.98e-171: 492: 39.33		CAV2_HUMAN (53-177): 5.12e-59: 183: 40.80