Interactor 1: PSN1 (P49769)
Presenilin-1 (PS-1) (EC 3.4.23.-) (Protein S182) [Cleaved into: Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12 (PS1-CTF12)]
Gene: Psen1

Interactor 2: PSN2 (Q61144)
Presenilin-2 (PS-2) (EC 3.4.23.-) [Cleaved into: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit]
Gene: Psen2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 15474363
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Presenilin~Presenilin
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000139 - Golgi membrane
GO:0001708 - cell fate specification
GO:0001756 - somitogenesis
GO:0001921 - positive regulation of receptor recycling
and 63 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 467
Mm

1 448
+ Hs
+ Hs
+ Mm
+ Hs
+ Rn
+ Dm
+ Ce

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Last updated: 15 Jul 2024