HitPredict

Interactor 1: RBP2 (P49792)
E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) (p270)
Gene: RANBP2

Interactor 2: NXF1 (Q9UBU9)
Nuclear RNA export factor 1 (Tip-associated protein) (Tip-associating protein) (mRNA export factor TAP)
Gene: NXF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.702

Property	Details
Experiments	31375530, 10668806, 16314397, 18596238, 20123736
Identification Methods	fluorescent resonance energy transfer, affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005643 - nuclear pore GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 1 others more... GO:0042405 - nuclear inclusion body
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 3224 Hs			1 619
+	Hs
		1305510 RGPD5_HUMAN (2355-3076): 9.38e-42: 172: 16.89		NXF1_HUMAN (1-619): 0: 929: 100.00
+	Hs
		483413 RGPD1_HUMAN (1026-1514): 2.56e-27: 125: 21.86		NXF1_HUMAN (1-619): 0: 929: 100.00
+	Hs
		152806 RGPD8_HUMAN (2355-3064): 2.79e-42: 174: 17.03		NXF2_HUMAN (11-619): 0: 840: 59.11
+	Hs
		1305503 RGPD5_HUMAN (2355-3076): 9.38e-42: 172: 16.89		NXF2_HUMAN (11-619): 0: 840: 59.11
+	Dm
		1353485 NU153_DROME (1294-1955): 2.11e-30: 135: 17.80		NXF1_DROME (20-619): 0: 562: 30.49
+	Ce
		1197298 Q86G90_CAEEL (2805-3079): 1.65e-31: 137: 24.10		NXF1_CAEEL (127-617): 4.08e-158: 469: 27.70