Protein: EPIPL
Epiplakin (450 kDa epidermal antigen)

Gene: EPIPL, EPPK1
Organism: Homo sapiens
Interactions: 191
UniProt ID: P58107

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005198 - structural molecule activity
GO:0005737 - cytoplasm
GO:0005856 - cytoskeleton
GO:0005923 - bicellular tight junction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

443432

VIME
Vimentin

5

20

High-throughput

0.718

High

885296

CDK15
Cyclin-dependent kinase 15

2

9

High-throughput

0.628

High

885333

FCF1
rRNA-processing protein FCF1 homolog

2

2

High-throughput

0.628

High

408769

K1C18
Keratin, type I cytoskeletal 18

2

20

High-throughput

0.611

High

885245

CUL3
Cullin-3

2

12

High-throughput

0.611

High

885329

DD19B
ATP-dependent RNA helicase DDX19B

2

7

High-throughput

0.611

High

885236

FGL1
Fibrinogen-like protein 1

3

1

High-throughput

0.609

High

885305

RBM24
RNA-binding protein 24

3

6

High-throughput

0.609

High

528852

CFTR
Cystic fibrosis transmembrane conductance regulator

2

9

High-throughput

0.601

High

646760

1433T
14-3-3 protein theta

2

20

High-throughput

0.601

High

227008

PRKN
E3 ubiquitin-protein ligase parkin

2

11

High-throughput

0.584

High

885322

TB22B
TBC1 domain family member 22B

2

6

High-throughput

0.574

High

563817

ZSC20
Zinc finger and SCAN domain-containing protein 20

2

3

High-throughput

0.558

High

213934

KRT86
Keratin, type II cuticular Hb6

1

19

High-throughput

0.536

High

318791

K2C75
Keratin, type II cytoskeletal 75

1

18

High-throughput

0.536

High

359323

K1C14
Keratin, type I cytoskeletal 14

1

20

High-throughput

0.536

High

369273

ESR1
Estrogen receptor

1

19

High-throughput

0.536

High

386405

P53
Cellular tumor antigen p53

1

7

High-throughput

0.536

High

422370

NFM
Neurofilament medium polypeptide

1

20

High-throughput

0.536

High

444531

K2C7
Keratin, type II cytoskeletal 7

1

18

High-throughput

0.536

High

517744

K2C3
Keratin, type II cytoskeletal 3

1

20

High-throughput

0.536

High

565905

AATC
Aspartate aminotransferase, cytoplasmic

1

5

High-throughput

0.536

High

686627

CCR1
C-C chemokine receptor type 1

1

6

High-throughput

0.536

High

791432

HD
Huntingtin

1

4

High-throughput

0.536

High

821534

PTSS1
Phosphatidylserine synthase 1

1

4

High-throughput

0.536

High

885226

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.536

High

885228

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

5

High-throughput

0.536

High

885234

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

885244

SNW1
SNW domain-containing protein 1

1

4

High-throughput

0.536

High

885247

KT33B
Keratin, type I cuticular Ha3-II

1

20

High-throughput

0.536

High

885248

K1H2
Keratin, type I cuticular Ha2

1

20

High-throughput

0.536

High

885251

K2C72
Keratin, type II cytoskeletal 72

1

20

High-throughput

0.536

High

885254

K1H1
Keratin, type I cuticular Ha1

1

20

High-throughput

0.536

High

885257

LRC10
Leucine-rich repeat-containing protein 10

1

4

High-throughput

0.536

High

885258

MRCKA
Serine/threonine-protein kinase MRCK alpha

1

17

High-throughput

0.536

High

885266

K1C27
Keratin, type I cytoskeletal 27

1

20

High-throughput

0.536

High

885269

K2C73
Keratin, type II cytoskeletal 73

1

20

High-throughput

0.536

High

885274

K2C78
Keratin, type II cytoskeletal 78

1

20

High-throughput

0.536

High

885287

PIGT
GPI transamidase component PIG-T

1

2

High-throughput

0.536

High

885288

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

3

High-throughput

0.536

High

885293

CERS2
Ceramide synthase 2

1

3

High-throughput

0.536

High

885299

CDC5L
Cell division cycle 5-like protein

1

7

High-throughput

0.536

High

885309

K1C23
Keratin, type I cytoskeletal 23

1

20

High-throughput

0.536

High

885321

KRT82
Keratin, type II cuticular Hb2

1

19

High-throughput

0.536

High

885316

WDR76
WD repeat-containing protein 76

2

20

High-throughput

0.533

High

885319

ANLN
Anillin

2

9

High-throughput

0.533

High

885278

POC5
Centrosomal protein POC5

2

5

Small-scale

0.521

High

607619

NDKB
Nucleoside diphosphate kinase B

1

2

High-throughput

0.515

High

779117

CCNF
Cyclin-F

1

5

High-throughput

0.515

High

885222

ARF6
ADP-ribosylation factor 6

1

4

High-throughput

0.515

High

885255

T22D1
TSC22 domain family protein 1

1

3

High-throughput

0.515

High

885300

PHB2
Prohibitin-2

1

1

High-throughput

0.515

High

885327

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

2

High-throughput

0.515

High

885328

CLC4E
C-type lectin domain family 4 member E

1

2

High-throughput

0.515

High

885335

TRAF6
TNF receptor-associated factor 6

1

14

High-throughput

0.515

High

200816

ZSC12
Zinc finger and SCAN domain-containing protein 12

2

2

High-throughput

0.504

High

885219

SUMO2
Small ubiquitin-related modifier 2

1

5

High-throughput

0.501

High

885336

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

8

Small-scale

0.501

High

328786

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.493

High

885331

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.493

High

239884

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

6

High-throughput

0.489

High

303676

OR2A4
Olfactory receptor 2A4

1

3

High-throughput

0.489

High

840625

ASCL1
Achaete-scute homolog 1

1

4

High-throughput

0.489

High

882712

STX17
Syntaxin-17

1

4

High-throughput

0.489

High

885232

GCYA1
Guanylate cyclase soluble subunit alpha-1

1

1

High-throughput

0.489

High

885256

CR021
UPF0711 protein C18orf21

1

3

High-throughput

0.489

High

885268

ZC3C1
Zinc finger C3HC-type protein 1

1

3

High-throughput

0.489

High

885270

CERS3
Ceramide synthase 3

1

3

High-throughput

0.489

High

885290

SARAF
Store-operated calcium entry-associated regulatory factor

1

2

High-throughput

0.489

High

885295

F227B
Protein FAM227B

1

2

High-throughput

0.489

High

885302

WDR83
WD repeat domain-containing protein 83

1

13

High-throughput

0.489

High

885323

KLH11
Kelch-like protein 11

1

3

High-throughput

0.489

High

148591

CTRO
Citron Rho-interacting kinase

1

8

High-throughput

0.479

High

181596

CFLAR
CASP8 and FADD-like apoptosis regulator

1

1

High-throughput

0.479

High

209817

PRC1
Protein regulator of cytokinesis 1

1

14

High-throughput

0.479

High

232829

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

6

High-throughput

0.479

High

255631

OBSL1
Obscurin-like protein 1

1

17

High-throughput

0.479

High

260540

TP4A3
Protein tyrosine phosphatase type IVA 3

1

11

High-throughput

0.479

High

278011

PIAS1
E3 SUMO-protein ligase PIAS1

1

5

High-throughput

0.479

High

294190

TRPM2
Transient receptor potential cation channel subfamily M member 2

1

2

High-throughput

0.479

High

301701

TRI37
E3 ubiquitin-protein ligase TRIM37

1

14

High-throughput

0.479

High

346357

MYC
Myc proto-oncogene protein

1

9

High-throughput

0.479

High

397873

ISG15
Ubiquitin-like protein ISG15

1

12

High-throughput

0.479

High

409039

K2C8
Keratin, type II cytoskeletal 8

1

18

High-throughput

0.479

High

445837

ROS1
Proto-oncogene tyrosine-protein kinase ROS

1

14

High-throughput

0.479

High

453241

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

4

High-throughput

0.479

High

475541

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

11

Small-scale

0.479

High

487276

ANDR
Androgen receptor

1

18

High-throughput

0.479

High

521243

SKI
Ski oncogene

1

3

Small-scale

0.479

High

525884

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

531096

EF2
Elongation factor 2

1

5

High-throughput

0.479

High

584357

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

2

High-throughput

0.479

High

591292

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

3

High-throughput

0.479

High

595167

LMNB1
Lamin-B1

1

20

High-throughput

0.479

High

758169

CDN1A
Cyclin-dependent kinase inhibitor 1

1

1

High-throughput

0.479

High

793864

MATR3
Matrin-3

1

2

High-throughput

0.479

High

807656

MAP1B
Microtubule-associated protein 1B

1

12

High-throughput

0.479

High

832278

MCM2
DNA replication licensing factor MCM2

1

9

High-throughput

0.479

High

874744

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

885217

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

12

High-throughput

0.479

High

885218

RHOA
Transforming protein RhoA

1

13

High-throughput

0.479

High

885223

RHOB
Rho-related GTP-binding protein RhoB

1

15

High-throughput

0.479

High

885224

H4
Histone H4

1

5

High-throughput

0.479

High

885225

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

12

High-throughput

0.479

High

885227

KCNJ2
Inward rectifier potassium channel 2

1

3

Small-scale

0.479

High

885229

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

18

High-throughput

0.479

High

885231

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

12

High-throughput

0.479

High

885238

MERTK
Tyrosine-protein kinase Mer

1

12

High-throughput

0.479

High

885240

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

12

High-throughput

0.479

High

885241

TIF1B
Transcription intermediary factor 1-beta

1

8

High-throughput

0.479

High

885242

G3BP1
Ras GTPase-activating protein-binding protein 1

1

3

High-throughput

0.479

High

885246

CUL4A
Cullin-4A

1

12

High-throughput

0.479

High

885249

NBR1
Next to BRCA1 gene 1 protein

1

3

High-throughput

0.479

High

885250

CUL7
Cullin-7

1

12

High-throughput

0.479

High

885253

KIF14
Kinesin-like protein KIF14

1

9

High-throughput

0.479

High

885259

FTM
Protein fantom

1

20

High-throughput

0.479

High

885260

VIR
Protein virilizer homolog

1

3

High-throughput

0.479

High

885261

PRP8
Pre-mRNA-processing-splicing factor 8

1

2

High-throughput

0.479

High

885263

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

13

Small-scale

0.479

High

885264

MOB3C
MOB kinase activator 3C

1

4

High-throughput

0.479

High

885267

ZN598
E3 ubiquitin-protein ligase ZNF598

1

6

High-throughput

0.479

High

885273

CNTRB
Centrobin

1

18

High-throughput

0.479

High

885277

CE120
Centrosomal protein of 120 kDa

1

20

High-throughput

0.479

High

885281

NUDC2
NudC domain-containing protein 2

1

4

High-throughput

0.479

High

885283

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

8

High-throughput

0.479

High

885284

AKAP1
A-kinase anchor protein 1, mitochondrial

1

2

High-throughput

0.479

High

885286

FGF11
Fibroblast growth factor 11

1

1

High-throughput

0.479

High

885291

GCP3
Gamma-tubulin complex component 3

1

1

High-throughput

0.479

High

885301

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

10

High-throughput

0.479

High

885303

INP5K
Inositol polyphosphate 5-phosphatase K

1

2

High-throughput

0.479

High

885306

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

14

High-throughput

0.479

High

885307

RNF17
RING finger protein 17

1

2

High-throughput

0.479

High

885311

CCDC8
Coiled-coil domain-containing protein 8

1

6

High-throughput

0.479

High

885312

CHM4B
Charged multivesicular body protein 4b

1

6

High-throughput

0.479

High

885313

PKHA4
Pleckstrin homology domain-containing family A member 4

1

18

High-throughput

0.479

High

885315

ECT2
Protein ECT2

1

19

High-throughput

0.479

High

885317

RHOF
Rho-related GTP-binding protein RhoF

1

17

High-throughput

0.479

High

885318

E41LA
Band 4.1-like protein 4A

1

10

High-throughput

0.479

High

885320

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

8

High-throughput

0.479

High

885324

PIHD1
PIH1 domain-containing protein 1

1

3

High-throughput

0.479

High

885325

WRP73
WD repeat-containing protein WRAP73

1

15

High-throughput

0.479

High

885326

HDAC6
Histone deacetylase 6

1

10

High-throughput

0.479

High

885330

SRRM2
Serine/arginine repetitive matrix protein 2

1

13

High-throughput

0.479

High

885337

NEMO
NF-kappa-B essential modulator

1

20

High-throughput

0.479

High

885282

CLC4D
C-type lectin domain family 4 member D

1

2

High-throughput

0.470

High

152822

TRDMT
tRNA

1

0

High-throughput

0.458

High

273749

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

378506

OAT
Ornithine aminotransferase, mitochondrial

1

0

High-throughput

0.458

High

881606

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

885271

ARMC8
Armadillo repeat-containing protein 8

1

0

High-throughput

0.458

High

885272

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

Small-scale

0.458

High

885314

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

0

High-throughput

0.458

High

580127

K2C4
Keratin, type II cytoskeletal 4

1

20

High-throughput

0.445

High

885239

STK4
Serine/threonine-protein kinase 4

1

19

High-throughput

0.445

High

885243

SQSTM
Sequestosome-1

1

14

High-throughput

0.445

High

131709

BCL9
B-cell CLL/lymphoma 9 protein

1

3

Small-scale

0.437

High

156393

RGRF2
Ras-specific guanine nucleotide-releasing factor 2

1

14

High-throughput

0.437

High

177854

TMPS2
Transmembrane protease serine 2

1

1

High-throughput

0.437

High

308547

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.437

High

329553

AGR2
Anterior gradient protein 2 homolog

1

5

High-throughput

0.437

High

391623

H2A1B
Histone H2A type 1-B/E

1

2

High-throughput

0.437

High

674375

UFO
Tyrosine-protein kinase receptor UFO

1

13

High-throughput

0.437

High

707567

H2B1B
Histone H2B type 1-B

1

10

High-throughput

0.437

High

738188

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

5

High-throughput

0.437

High

783313

M3K8
Mitogen-activated protein kinase kinase kinase 8

1

10

High-throughput

0.437

High

885220

WDR5
WD repeat-containing protein 5

1

15

High-throughput

0.437

High

885221

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.437

High

885230

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.437

High

885233

KIF23
Kinesin-like protein KIF23

1

15

High-throughput

0.437

High

885235

CTSL2
CTD small phosphatase-like protein 2

1

1

Small-scale

0.437

High

885252

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.437

High

885265

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

6

High-throughput

0.437

High

885276

NKAI3
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3

1

5

High-throughput

0.437

High

885279

NHLC2
NHL repeat-containing protein 2

1

2

High-throughput

0.437

High

885280

DEP1B
DEP domain-containing protein 1B

1

2

High-throughput

0.437

High

885285

ESR2
Estrogen receptor beta

1

18

High-throughput

0.437

High

885292

SPDLY
Protein Spindly

1

18

High-throughput

0.437

High

885294

AURKB
Aurora kinase B

1

14

High-throughput

0.437

High

885297

CIC
Protein capicua homolog

1

19

High-throughput

0.437

High

885304

CP250
Centrosome-associated protein CEP250

1

20

High-throughput

0.437

High

885308

FACD2
Fanconi anemia group D2 protein

1

6

High-throughput

0.437

High

885332

AAR2
Protein AAR2 homolog

1

1

High-throughput

0.437

High

885334

TRRAP
Transformation/transcription domain-associated protein

1

5

High-throughput

0.437

High

47336

A0A6Q8PFP9
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein

1

5

High-throughput

0.407

High

717606

BMI1
Polycomb complex protein BMI-1

1

13

High-throughput

0.407

High

885262

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

3

High-throughput

0.407

High

885310

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

12

High-throughput

0.407

High

885275

CCD82
Coiled-coil domain-containing protein 82

1

0

High-throughput

0.279

Low

885289

PINX1
PIN2/TERF1-interacting telomerase inhibitor 1

1

0

High-throughput

0.249

Low

885237

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.232

Low

885298

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024