HitPredict

Interactor 1: DNLI4 (P49917)
DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4)
Gene: LIG4

Interactor 2: APLF (Q8IW19)
Aprataxin and PNK-like factor (EC 3.1.-.-) (Apurinic-apyrimidinic endonuclease APLF) (PNK and APTX-like FHA domain-containing protein) (XRCC1-interacting protein 1)
Gene: APLF

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	26186194, 28514442, 33961781, 17396150, 23178593
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, filter binding
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000012 - single strand break repair GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006302 - double-strand break repair GO:0006303 - double-strand break repair via nonhomologous end joining
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 911 Hs			1 511
+	Hs
		836748 DNLI3_HUMAN (3-737): 0: 586: 21.33		APLF_HUMAN (1-511): 0: 843: 100.00