Interactor 1: DNLI4 (P49917)
DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4)
Gene: LIG4

Interactor 2: NHEJ1 (Q9H9Q4)
Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor)
Gene: NHEJ1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.55 0.622

The method score is based on:

Property Details
Experiments 17567543, 31548606, 16439205
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down, coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005958 - DNA-dependent protein kinase-DNA ligase 4 complex
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0007417 - central nervous system development
and 4 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024