Protein: GMPPB
Mannose-1-phosphate guanylyltransferase catalytic subunit beta (EC 2.7.7.13) (GDP-mannose pyrophosphorylase B) (GTP-mannose-1-phosphate guanylyltransferase beta)

Gene: GMPPB
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q9Y5P6

Gene Ontology (top 5):
GO:0004475 - mannose-1-phosphate guanylyltransferase (GTP) activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006486 - protein glycosylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1394229

GMPPA
Mannose-1-phosphate guanylyltransferase regulatory subunit alpha

8

13

High-throughput

0.973

High

1433376

GOLP3
Golgi phosphoprotein 3

4

2

High-throughput

0.691

High

253532

ANM3
Protein arginine N-methyltransferase 3

3

1

High-throughput

0.667

High

325507

CCNB2
G2/mitotic-specific cyclin-B2

3

1

High-throughput

0.667

High

1287505

PRUN1
Exopolyphosphatase PRUNE1

3

0

High-throughput

0.638

High

1349734

P4K2B
Phosphatidylinositol 4-kinase type 2-beta

3

0

High-throughput

0.638

High

180446

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

1

High-throughput

0.606

High

833064

EIF2D
Eukaryotic translation initiation factor 2D

2

0

High-throughput

0.585

High

1034956

PYRD
Dihydroorotate dehydrogenase

2

0

High-throughput

0.585

High

1309122

GLCTK
Glycerate kinase

2

0

High-throughput

0.580

High

1095967

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

17

High-throughput

0.536

High

1415143

TBB2B
Tubulin beta-2B chain

1

1

High-throughput

0.536

High

1334148

TXND5
Thioredoxin domain-containing protein 5

2

1

High-throughput

0.526

High

1186869

KR196
Keratin-associated protein 19-6

1

0

High-throughput

0.513

High

1347488

CEP76
Centrosomal protein of 76 kDa

1

0

High-throughput

0.513

High

1439316

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.513

High

1447963

SHLB2
Endophilin-B2

1

0

High-throughput

0.513

High

908799

MAT1
CDK-activating kinase assembly factor MAT1

1

1

High-throughput

0.489

High

124667

EYA2
Protein phosphatase EYA2

1

1

High-throughput

0.479

High

294590

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.479

High

538180

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

831723

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

877054

KC1A
Casein kinase I isoform alpha

1

1

High-throughput

0.479

High

1178487

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

1256278

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

1397607

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.479

High

1435508

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

1460563

HACL1
2-hydroxyacyl-CoA lyase 1

1

4

High-throughput

0.479

High

1289413

Q86UY0
Thioredoxin domain-containing protein 5

1

1

High-throughput

0.470

High

1152507

T22D1
TSC22 domain family protein 1

1

0

High-throughput

0.458

High

1421291

MTMRC
Myotubularin-related protein 12

1

0

High-throughput

0.458

High

142448

PEX7
Peroxisomal targeting signal 2 receptor

1

4

High-throughput

0.445

High

967188

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

1

High-throughput

0.445

High

1209849

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

1366327

LPAR1
Lysophosphatidic acid receptor 1

1

4

High-throughput

0.445

High

1420133

NMNA2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2

1

1

High-throughput

0.445

High

1449942

DDX28
Probable ATP-dependent RNA helicase DDX28

1

1

High-throughput

0.445

High

1462725

GAB2
GRB2-associated-binding protein 2

1

1

High-throughput

0.445

High

373624

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.437

High

590143

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

769627

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

1100588

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.437

High

261346

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.426

High

598799

ANFB
Natriuretic peptides B

1

0

High-throughput

0.426

High

896479

ERF
ETS domain-containing transcription factor ERF

1

0

High-throughput

0.426

High

1382680

P33MX
Putative monooxygenase p33MONOX

1

0

High-throughput

0.426

High

628668

CAP7
Azurocidin

1

1

High-throughput

0.407

High

1104176

RM49
Large ribosomal subunit protein mL49

1

1

High-throughput

0.407

High

1322516

PUSL1
tRNA pseudouridine synthase-like 1

2

0

High-throughput

0.318

High

1271236

DPPA4
Developmental pluripotency-associated protein 4

2

0

High-throughput

0.316

High

1245952

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.279

Low

1491723

KPTN
KICSTOR complex protein kaptin

1

0

High-throughput

0.279

Low

418544

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

330386

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.232

Low

1447621

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025