Interactor 1: MRE11 (P49959)
Double-strand break repair protein MRE11 (EC 3.1.-.-) (Meiotic recombination 11 homolog 1) (MRE11 homolog 1) (Meiotic recombination 11 homolog A) (MRE11 homolog A)
Gene: MRE11
Interactor 2: CTIP (Q99708)
DNA endonuclease RBBP8 (EC 3.1.-.-) (CtBP-interacting protein) (CtIP) (Retinoblastoma-binding protein 8) (RBBP-8) (Retinoblastoma-interacting protein and myosin-like) (RIM) (Sporulation in the absence of SPO11 protein 2 homolog) (SAE2)
Gene: RBBP8
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 0.55 | 0.722 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22231403, 25349192, 26807646, 26387952, 27561354, 31636387, 33723063, 34921745, 25558984, 21052091 |
| Identification Methods | affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000014 - single-stranded DNA endodeoxyribonuclease activity GO:0000724 - double-strand break repair via homologous recombination GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006281 - DNA repair and 5 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
