Protein: TBL1X
F-box-like/WD repeat-containing protein TBL1X (SMAP55) (Transducin beta-like protein 1X) (Transducin-beta-like protein 1, X-linked)

Gene: TBL1X
Organism: Homo sapiens
Interactions: 121
UniProt ID: O60907

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

245633

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

4

16

Small-scale

0.890

High

245630

TBL1Y
F-box-like/WD repeat-containing protein TBL1Y

2

16

High-throughput

0.811

High

245546

TBL1X
F-box-like/WD repeat-containing protein TBL1X

2

15

Small-scale

0.799

High

245598

GPS2
G protein pathway suppressor 2

7

2

Small-scale

0.755

High

245635

UBP44
Ubiquitin carboxyl-terminal hydrolase 44

2

11

Small-scale

0.754

High

245548

NCOR1
Nuclear receptor corepressor 1

8

20

Small-scale

0.753

High

177148

HDAC3
Histone deacetylase 3

8

16

Small-scale

0.753

High

245652

NCOR2
Nuclear receptor corepressor 2

5

20

Small-scale

0.726

High

245613

WDR59
GATOR2 complex protein WDR59

2

18

High-throughput

0.726

High

245605

DDB1
DNA damage-binding protein 1

1

8

Small-scale

0.724

High

245651

T22D4
TSC22 domain family protein 4

3

4

High-throughput

0.667

High

245619

HORM2
HORMA domain-containing protein 2

1

0

High-throughput

0.656

High

245649

HDAC5
Histone deacetylase 5

3

20

Small-scale

0.656

High

245590

FOXK2
Forkhead box protein K2

2

10

Small-scale

0.649

High

245576

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

3

Small-scale

0.647

High

245581

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

4

Small-scale

0.647

High

245589

UBC9
SUMO-conjugating enzyme UBC9

1

6

Small-scale

0.647

High

245586

H4
Histone H4

3

5

Small-scale

0.646

High

245567

CTNB1
Catenin beta-1

3

11

Small-scale

0.640

High

245617

MKX
Homeobox protein Mohawk

2

5

High-throughput

0.628

High

245625

UB2E3
Ubiquitin-conjugating enzyme E2 E3

1

4

Small-scale

0.618

High

245572

ARL3
ADP-ribosylation factor-like protein 3

2

7

High-throughput

0.606

High

245556

THB
Thyroid hormone receptor beta

2

20

Small-scale

0.602

High

245607

H2B2E
Histone H2B type 2-E

2

5

Small-scale

0.595

High

245580

MECP2
Methyl-CpG-binding protein 2

2

5

Small-scale

0.594

High

245552

PAI2
Plasminogen activator inhibitor 2

2

4

High-throughput

0.574

High

245608

LRC36
Leucine-rich repeat-containing protein 36

2

5

High-throughput

0.574

High

245547

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

2

10

High-throughput

0.558

High

245632

TINF2
TERF1-interacting nuclear factor 2

1

0

High-throughput

0.543

High

208024

HAIR
Lysine-specific demethylase hairless

1

2

High-throughput

0.541

High

234680

DLX3
Homeobox protein DLX-3

1

5

High-throughput

0.541

High

245582

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.541

High

146778

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

2

High-throughput

0.536

High

245550

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.536

High

245565

TKT
Transketolase

1

3

High-throughput

0.536

High

245579

ERF
ETS domain-containing transcription factor ERF

1

15

High-throughput

0.536

High

245594

SSRP1
FACT complex subunit SSRP1

1

20

High-throughput

0.536

High

245602

FHL2
Four and a half LIM domains protein 2

1

5

High-throughput

0.536

High

245609

EFMT2
EEF1A lysine methyltransferase 2

1

1

High-throughput

0.536

High

245622

HDAC7
Histone deacetylase 7

1

20

High-throughput

0.536

High

245631

KLDC3
Kelch domain-containing protein 3

1

5

High-throughput

0.536

High

245637

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.536

High

157841

KLF11
Krueppel-like factor 11

1

14

High-throughput

0.515

High

245562

DNJB1
DnaJ homolog subfamily B member 1

1

10

High-throughput

0.515

High

245627

IL17F
Interleukin-17F

1

0

High-throughput

0.513

High

245634

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

0

High-throughput

0.513

High

245555

THA
Thyroid hormone receptor alpha

1

20

Small-scale

0.501

High

245612

H2A2A
Histone H2A type 2-A

1

6

Small-scale

0.501

High

245614

H32
Histone H3.2

1

11

Small-scale

0.501

High

245642

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

1

8

Small-scale

0.501

High

245577

DGKG
Diacylglycerol kinase gamma

1

2

High-throughput

0.489

High

245626

I17RA
Interleukin-17 receptor A

1

1

High-throughput

0.489

High

245628

TCPQM
T-complex protein 1 subunit theta-like 2

1

20

High-throughput

0.489

High

245643

HAOX2
2-Hydroxyacid oxidase 2

1

1

High-throughput

0.489

High

245650

CCL26
C-C motif chemokine 26

1

1

High-throughput

0.489

High

245571

ARL2
ADP-ribosylation factor-like protein 2

1

7

High-throughput

0.481

High

245593

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

4

High-throughput

0.481

High

245646

DNJB4
DnaJ homolog subfamily B member 4

1

10

High-throughput

0.481

High

135057

NFIB
Nuclear factor 1 B-type

1

8

High-throughput

0.479

High

162254

XPO1
Exportin-1

1

12

High-throughput

0.479

High

170997

TBXT
T-box transcription factor T

1

4

High-throughput

0.479

High

211773

TLX3
T-cell leukemia homeobox protein 3

1

10

High-throughput

0.479

High

213284

TLX2
T-cell leukemia homeobox protein 2

1

7

High-throughput

0.479

High

231898

KDM1A
Lysine-specific histone demethylase 1A

1

8

High-throughput

0.479

High

243688

BRD4
Bromodomain-containing protein 4

1

15

High-throughput

0.479

High

245553

NFIC
Nuclear factor 1 C-type

1

16

High-throughput

0.479

High

245554

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

245557

MYOD1
Myoblast determination protein 1

1

1

High-throughput

0.479

High

245558

GATA1
Erythroid transcription factor

1

9

High-throughput

0.479

High

245559

PAX7
Paired box protein Pax-7

1

4

High-throughput

0.479

High

245560

GATA2
Endothelial transcription factor GATA-2

1

9

High-throughput

0.479

High

245561

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

9

High-throughput

0.479

High

245563

PAX6
Paired box protein Pax-6

1

3

High-throughput

0.479

High

245566

TLX1
T-cell leukemia homeobox protein 1

1

11

High-throughput

0.479

High

245568

HNF1B
Hepatocyte nuclear factor 1-beta

1

5

High-throughput

0.479

High

245569

SOX5
Transcription factor SOX-5

1

18

High-throughput

0.479

High

245570

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

245573

PPARG
Peroxisome proliferator-activated receptor gamma

1

20

High-throughput

0.479

High

245574

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

245575

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.479

High

245578

EMD
Emerin

1

2

Small-scale

0.479

High

245583

PAX9
Paired box protein Pax-9

1

3

High-throughput

0.479

High

245584

HDAC4
Histone deacetylase 4

1

20

High-throughput

0.479

High

245585

SOX10
Transcription factor SOX-10

1

20

High-throughput

0.479

High

245587

RBX1
E3 ubiquitin-protein ligase RBX1

1

2

Small-scale

0.479

High

245588

SKP1
S-phase kinase-associated protein 1

1

2

Small-scale

0.479

High

245591

TF65
Transcription factor p65

1

4

Small-scale

0.479

High

245592

HME1
Homeobox protein engrailed-1

1

2

High-throughput

0.479

High

245595

NFIA
Nuclear factor 1 A-type

1

13

High-throughput

0.479

High

245596

FOXI1
Forkhead box protein I1

1

9

High-throughput

0.479

High

245597

FOXL1
Forkhead box protein L1

1

9

High-throughput

0.479

High

245599

CTBP1
C-terminal-binding protein 1

1

6

Small-scale

0.479

High

245600

HDAC1
Histone deacetylase 1

1

19

High-throughput

0.479

High

245601

CUL4B
Cullin-4B

1

20

Small-scale

0.479

High

245603

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

14

High-throughput

0.479

High

245604

NFIX
Nuclear factor 1 X-type

1

14

High-throughput

0.479

High

245606

TBR1
T-box brain protein 1

1

4

High-throughput

0.479

High

245615

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.479

High

245616

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

4

Small-scale

0.479

High

245621

SP7
Transcription factor Sp7

1

13

High-throughput

0.479

High

245623

HDAC2
Histone deacetylase 2

1

19

High-throughput

0.479

High

245629

SIN3A
Paired amphipathic helix protein Sin3a

1

2

Small-scale

0.479

High

245636

SOX17
Transcription factor SOX-17

1

20

High-throughput

0.479

High

245638

NANOG
Homeobox protein NANOG

1

12

High-throughput

0.479

High

245644

VSX1
Visual system homeobox 1

1

4

High-throughput

0.479

High

245647

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

245648

RCOR1
REST corepressor 1

1

16

High-throughput

0.479

High

245549

PRDM1
PR domain zinc finger protein 1

1

0

High-throughput

0.458

High

245564

TEAD1
Transcriptional enhancer factor TEF-1

1

0

High-throughput

0.458

High

245624

LHX4
LIM/homeobox protein Lhx4

1

0

High-throughput

0.458

High

245639

CYBP
Calcyclin-binding protein

1

0

Small-scale

0.458

High

245640

GCM1
Chorion-specific transcription factor GCMa

1

0

High-throughput

0.458

High

245618

ZDH23
Palmitoyltransferase ZDHHC23

1

4

Small-scale

0.437

High

245641

ZDH18
Palmitoyltransferase ZDHHC18

1

3

Small-scale

0.437

High

245645

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

5

High-throughput

0.407

High

245610

CF141
Uncharacterized protein C6orf141

2

0

High-throughput

0.328

High

245611

SPT46
Spermatogenesis-associated protein 46

1

0

High-throughput

0.279

Low

245620

LY65B
Lymphocyte antigen 6 complex locus protein G5b

1

0

High-throughput

0.279

Low

245551

HPT
Haptoglobin

1

0

High-throughput

0.251

Low

216028

NRDC
Nardilysin

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024