HitPredict

Interactor 1: GDIB (P50395)
Rab GDP dissociation inhibitor beta (Rab GDI beta) (Guanosine diphosphate dissociation inhibitor 2) (GDI-2)
Gene: GDI2

Interactor 2: RAB18 (Q9NP72)
Ras-related protein Rab-18
Gene: RAB18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0007264 - small GTPase-mediated signal transduction GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 445 Hs			1 206
+	Hs
		678364 GDIA_HUMAN (1-444): 0: 714: 86.49		Q5W0J0_HUMAN (1-206): 5.54e-106: 303: 78.16
+	Hs
		838625 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB1A_HUMAN (1-200): 1.22e-82: 245: 43.84
+	Hs
		838683 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB1B_HUMAN (1-200): 8.72e-82: 243: 42.57
+	Hs
		678397 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB18_HUMAN (1-206): 1.38e-84: 250: 100.00
+	Mm
		838709 GDIA_MOUSE (1-444): 0: 717: 87.39		RAB1A_MOUSE (1-200): 1.22e-82: 245: 43.84
+	Hs
		678344 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB1A_HUMAN (1-200): 1.22e-82: 245: 43.84
+	Hs
		838673 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB8B_HUMAN (1-206): 4.08e-79: 236: 39.42
+	Hs
		678394 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB1B_HUMAN (1-200): 8.72e-82: 243: 42.57
+	Hs
		838616 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB8A_HUMAN (1-206): 1.3e-78: 235: 38.94
+	Hs
		838608 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB13_HUMAN (1-205): 1.44e-77: 232: 38.35
+	Hs
		838619 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB10_HUMAN (1-199): 1.27e-77: 232: 40.80
+	Hs
		678381 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB8B_HUMAN (1-206): 4.08e-79: 236: 39.42
+	Hs
		678336 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB8A_HUMAN (1-206): 1.3e-78: 235: 38.94
+	Hs
		678333 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB13_HUMAN (1-205): 1.44e-77: 232: 38.35
+	Hs
		678340 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB10_HUMAN (1-199): 1.27e-77: 232: 40.80
+	Hs
		838617 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB2A_HUMAN (9-187): 5.36e-55: 175: 50.00
+	Hs
		838669 GDIB_HUMAN (1-445): 0: 722: 100.00		RAB2B_HUMAN (9-191): 3.72e-54: 173: 48.40
+	Hs
		678338 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB2A_HUMAN (9-187): 5.36e-55: 175: 50.00
+	Hs
		678377 GDIA_HUMAN (1-444): 0: 714: 86.49		RAB2B_HUMAN (9-191): 3.72e-54: 173: 48.40
+	Dm
		183444 Q9VLB7_DROME (1-440): 0: 662: 67.80		O15971_DROME (9-199): 3.94e-49: 160: 43.81