HitPredict

Interactor 1: MTOR (P42345)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1) (Tyrosine-protein kinase mTOR) (EC 2.7.10.2)
Gene: MTOR

Interactor 2: YTHD2 (Q9Y5A9)
YTH domain-containing family protein 2 (DF2) (CLL-associated antigen KW-14) (High-glucose-regulated protein 8) (Renal carcinoma antigen NY-REN-2)
Gene: YTHDF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	39501047
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2549 Hs			1 579
+	Hs
		839356 MTOR_HUMAN (1-2549): 0: 2102: 100.00		YTHD1_HUMAN (1-579): 1.7e-139: 417: 62.20
+	Hs
		1008417 PRKDC_HUMAN (695-2548): 0: 686: 14.83		YTHD2_HUMAN (1-579): 1.25e-177: 516: 100.00
+	Hs
		1008327 PRKDC_HUMAN (695-2548): 0: 686: 14.83		YTHD1_HUMAN (1-579): 1.7e-139: 417: 62.20
+	Hs
		1400497 SMG1_HUMAN (1557-2531): 1.87e-123: 441: 18.35		YTHD2_HUMAN (1-579): 1.25e-177: 516: 100.00
+	Hs
		1280723 SMG1_HUMAN (1557-2531): 1.87e-123: 441: 18.35		YTHD3_HUMAN (1-562): 1.94e-150: 447: 65.56