Interactor 1: TOB1 (P50616)
Protein Tob1 (Transducer of erbB-2 1)
Gene: TOB1
Interactor 2: CNOT7 (Q9UIV1)
CCR4-NOT transcription complex subunit 7 (EC 3.1.13.4) (BTG1-binding factor 1) (CCR4-associated factor 1) (CAF-1) (Caf1a)
Gene: CNOT7
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.974 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18056425, 26186194, 28514442, 33961781, 10602502, 18377426, 31515488, 19276069, 21336257, 20595394 |
| Identification Methods | affinity chromatography technology, pull down, tandem affinity purification, two hybrid array, anti tag coimmunoprecipitation, molecular sieving, x-ray crystallography, isothermal titration calorimetry |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BTG~CAF1 |
| Common GO terms | GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0008285 - negative regulation of cell population proliferation GO:0030014 - CCR4-NOT complex and 2 others more... |
| Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs |  |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
