Protein: MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Bcl-2-related protein EAT/mcl1)

Gene: MCL1
Organism: Mus musculus
Interactions: 22
UniProt ID: P97287

Gene Ontology (top 5):
GO:0001836 - release of cytochrome c from mitochondria
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

956158

APR
Phorbol-12-myristate-13-acetate-induced protein 1

5

7

Small-scale

0.932

High

222625

B2L11
Bcl-2-like protein 11

5

16

Small-scale

0.920

High

139728

BAK
Bcl-2 homologous antagonist/killer

1

17

Small-scale

0.692

High

956157

BBC3
Bcl-2-binding component 3

1

7

Small-scale

0.692

High

936812

BID
BH3-interacting domain death agonist

1

10

Small-scale

0.647

High

956156

BMF
Bcl-2-modifying factor

1

6

Small-scale

0.647

High

956151

TRI17
E3 ubiquitin-protein ligase TRIM17

1

2

Small-scale

0.561

High

476762

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

2

High-throughput

0.501

High

956155

MK08
Mitogen-activated protein kinase 8

1

13

Small-scale

0.501

High

956162

GSK3B
Glycogen synthase kinase-3 beta

1

9

Small-scale

0.501

High

956148

HIF3A
Hypoxia-inducible factor 3-alpha

1

5

Small-scale

0.479

High

956149

STING
Stimulator of interferon genes protein

1

1

High-throughput

0.479

High

956150

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

3

Small-scale

0.479

High

956154

FBXW7
F-box/WD repeat-containing protein 7

1

4

Small-scale

0.479

High

956159

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

2

Small-scale

0.479

High

956160

SKP1
S-phase kinase-associated protein 1

1

1

Small-scale

0.479

High

956161

CUL1
Cullin-1

1

2

Small-scale

0.479

High

921498

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

Small-scale

0.458

High

956152

FACD2
Fanconi anemia group D2 protein homolog

1

0

High-throughput

0.458

High

371788

CFAD
Complement factor D

1

2

High-throughput

0.437

High

46394

SIM43
Small integral membrane protein 43

1

0

High-throughput

0.249

Low

956153

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024