HitPredict

Interactor 1: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Interactor 2: TPM4 (P67936)
Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)
Gene: TPM4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26209609
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 248
+	Hs
		451219 CDK9_HUMAN (1-372): 2.88e-147: 422: 100.00		TPM1_HUMAN (4-248): 1.43e-48: 163: 68.16
+	Hs
		418915 CDK9_HUMAN (1-372): 2.88e-147: 422: 100.00		TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39
+	Hs
		434362 CDK9_HUMAN (1-372): 2.88e-147: 422: 100.00		TPM2_HUMAN (4-248): 5.04e-42: 146: 69.39
+	Hs
		451193 CDK2_HUMAN (16-321): 4.46e-136: 391: 38.76		TPM1_HUMAN (4-248): 1.43e-48: 163: 68.16
+	Hs
		110795 CDK2_HUMAN (16-321): 4.46e-136: 391: 38.76		H7BYY1_HUMAN (1-248): 8.1e-49: 162: 77.82
+	Hs
		418881 CDK2_HUMAN (16-321): 4.46e-136: 391: 38.76		TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39
+	Hs
		625341 CDK2_HUMAN (16-321): 4.46e-136: 391: 38.76		TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00
+	Hs
		434344 CDK2_HUMAN (16-321): 4.46e-136: 391: 38.76		TPM2_HUMAN (4-248): 5.04e-42: 146: 69.39
+	Hs
		434345 MK03_HUMAN (1-359): 1.92e-131: 382: 30.36		TPM2_HUMAN (4-248): 5.04e-42: 146: 69.39