HitPredict

Interactor 1: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.729

Property	Details
Experiments	26496610, 31980649, 35271311, 34709266, 20585571, unassigned2173
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 548 Hs			1 482
+	Hs
		1038670 TCPH_HUMAN (9-538): 0: 564: 26.39		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		826651 TCPG_HUMAN (10-547): 0: 558: 28.21		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		826803 TCPG_HUMAN (10-547): 0: 558: 28.21		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		821200 TCPE_HUMAN (2-524): 0: 535: 29.62		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		821342 TCPE_HUMAN (2-524): 0: 535: 29.62		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		843190 TCPD_HUMAN (19-525): 0: 530: 28.24		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		177238 TCPQ_HUMAN (1-548): 0: 616: 100.00		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Hs
		177367 TCPH_HUMAN (9-538): 0: 564: 26.39		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Hs
		177233 TCPG_HUMAN (10-547): 0: 558: 28.21		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Sp
		140725 TCPE_SCHPO (16-527): 0: 606: 30.17		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Sc
		693035 TCPH_YEAST (7-542): 0: 534: 28.34		RPD3_YEAST (8-421): 0: 580: 61.48
+	Hs
		177231 TCPE_HUMAN (2-524): 0: 535: 29.62		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Hs
		177239 TCPD_HUMAN (19-525): 0: 530: 28.24		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Sp
		140638 TCPH_SCHPO (1-546): 0: 566: 28.34		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Sc
		792389 TCPH_YEAST (7-542): 0: 534: 28.34		HOS2_YEAST (10-411): 2.72e-171: 491: 50.00
+	Hs
		843079 TCPQ_HUMAN (1-548): 0: 616: 100.00		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		1306720 TCPH_HUMAN (9-538): 0: 564: 26.39		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		826927 TCPG_HUMAN (10-547): 0: 558: 28.21		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		821448 TCPE_HUMAN (2-524): 0: 535: 29.62		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		843419 TCPD_HUMAN (19-525): 0: 530: 28.24		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78