HitPredict

Interactor 1: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36517590
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 548 Hs			1 746
+	Mm
		792275 TCPQ_MOUSE (1-548): 0: 617: 96.90		Q6AXH7_MOUSE (1-746): 0: 832: 96.41
+	Hs
		1080275 TCPH_HUMAN (9-538): 0: 564: 26.39		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		826679 TCPG_HUMAN (10-547): 0: 558: 28.21		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Mm
		945919 TCPH_MOUSE (9-546): 0: 573: 26.92		Q6AXH7_MOUSE (1-746): 0: 832: 96.41
+	Hs
		821226 TCPE_HUMAN (2-524): 0: 535: 29.62		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Hs
		843212 TCPD_HUMAN (19-525): 0: 530: 28.24		EZH2_HUMAN (1-746): 0: 862: 100.00
+	Mm
		945989 TCPG_MOUSE (10-547): 0: 557: 27.66		Q6AXH7_MOUSE (1-746): 0: 832: 96.41
+	Mm
		945948 TCPD_MOUSE (2-525): 0: 536: 27.90		Q6AXH7_MOUSE (1-746): 0: 832: 96.41
+	Hs
		843051 TCPQ_HUMAN (1-548): 0: 616: 100.00		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Hs
		203647 TCPQ_HUMAN (1-548): 0: 616: 100.00		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90
+	Sc
		755775 TCPH_YEAST (7-542): 0: 534: 28.34		SET1_YEAST (205-733): 1.13e-84: 292: 16.01
+	Hs
		1296406 TCPH_HUMAN (9-538): 0: 564: 26.39		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		1306682 TCPH_HUMAN (9-538): 0: 564: 26.39		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Hs
		826825 TCPG_HUMAN (10-547): 0: 558: 28.21		EHMT2_HUMAN (467-732): 1.91e-68: 247: 24.21
+	Hs
		826887 TCPG_HUMAN (10-547): 0: 558: 28.21		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Hs
		203775 TCPH_HUMAN (9-538): 0: 564: 26.39		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90
+	Hs
		203640 TCPG_HUMAN (10-547): 0: 558: 28.21		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90
+	Hs
		821409 TCPE_HUMAN (2-524): 0: 535: 29.62		SUV92_HUMAN (447-734): 5.41e-74: 247: 24.10
+	Hs
		203639 TCPE_HUMAN (2-524): 0: 535: 29.62		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90
+	Hs
		203648 TCPD_HUMAN (19-525): 0: 530: 28.24		SUV91_HUMAN (354-731): 2.25e-71: 240: 19.90