Protein: ITCH
E3 ubiquitin-protein ligase Itchy homolog (Itch) (EC 2.3.2.26) (Atrophin-1-interacting protein 4) (AIP4) (HECT-type E3 ubiquitin transferase Itchy homolog) (NFE2-associated polypeptide 1) (NAPP1)

Gene: ITCH
Organism: Homo sapiens
Interactions: 307
UniProt ID: Q96J02

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0002669 - positive regulation of T cell anergy
GO:0002870 - T cell anergy
GO:0004842 - ubiquitin-protein transferase activity
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

932560

UB2L3
Ubiquitin-conjugating enzyme E2 L3

20

20

Small-scale

0.988

High

1294834

ITCH
E3 ubiquitin-protein ligase Itchy homolog

16

14

Small-scale

0.985

High

476205

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

7

20

Small-scale

0.954

High

919827

UB2D2
Ubiquitin-conjugating enzyme E2 D2

6

20

Small-scale

0.942

High

849411

UB2D1
Ubiquitin-conjugating enzyme E2 D1

4

20

Small-scale

0.888

High

895882

UB2D3
Ubiquitin-conjugating enzyme E2 D3

4

20

Small-scale

0.888

High

275221

GRAP2
GRB2-related adapter protein 2

3

16

High-throughput

0.861

High

1294856

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

3

15

High-throughput

0.861

High

1294835

UB2E2
Ubiquitin-conjugating enzyme E2 E2

3

20

Small-scale

0.858

High

828008

UB2R1
Ubiquitin-conjugating enzyme E2 R1

3

20

Small-scale

0.845

High

851871

UB2E1
Ubiquitin-conjugating enzyme E2 E1

3

20

Small-scale

0.845

High

542908

BRAF
Serine/threonine-protein kinase B-raf

2

13

Small-scale

0.819

High

1262928

RASF5
Ras association domain-containing protein 5

2

4

Small-scale

0.806

High

1294855

TOLIP
Toll-interacting protein

2

1

High-throughput

0.789

High

896355

UBE2K
Ubiquitin-conjugating enzyme E2 K

2

20

Small-scale

0.778

High

908265

UB2G1
Ubiquitin-conjugating enzyme E2 G1

2

20

Small-scale

0.778

High

159084

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

2

20

High-throughput

0.768

High

808850

YAP1
Transcriptional coactivator YAP1

2

17

Small-scale

0.754

High

1294877

WWOX
WW domain-containing oxidoreductase

2

1

Small-scale

0.754

High

1294878

PD1L1
Programmed cell death 1 ligand 1

2

6

Small-scale

0.754

High

1294858

TXNIP
Thioredoxin-interacting protein

7

20

Small-scale

0.752

High

1234600

ARRD1
Arrestin domain-containing protein 1

7

20

Small-scale

0.749

High

1229716

SPART
Spartin

7

10

Small-scale

0.747

High

175909

P73
Tumor protein p73

6

15

Small-scale

0.743

High

181634

CFLAR
CASP8 and FADD-like apoptosis regulator

8

3

Small-scale

0.741

High

1294857

P63
Tumor protein 63

6

15

Small-scale

0.738

High

1294890

RNF11
RING finger protein 11

6

14

Small-scale

0.737

High

325853

LATS1
Serine/threonine-protein kinase LATS1

6

15

Small-scale

0.736

High

1285047

ARRD3
Arrestin domain-containing protein 3

5

20

Small-scale

0.727

High

374703

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

16

Small-scale

0.724

High

412307

FYN
Tyrosine-protein kinase Fyn

1

14

Small-scale

0.724

High

1078893

ITSN1
Intersectin-1

1

9

Small-scale

0.724

High

1294845

SH3G2
Endophilin-A1

4

10

Small-scale

0.709

High

1084573

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

4

20

High-throughput

0.703

High

1079771

EREP1
Endosomal transmembrane epsin interactor 1

4

14

Small-scale

0.701

High

895710

CXCR4
C-X-C chemokine receptor type 4

4

5

Small-scale

0.698

High

1282371

WBP2
WW domain-binding protein 2

4

7

Small-scale

0.697

High

1294872

TMM51
Transmembrane protein 51

4

5

High-throughput

0.696

High

167384

SMAD7
Mothers against decapentaplegic homolog 7

4

20

Small-scale

0.691

High

833642

NUMB
Protein numb homolog

3

2

Small-scale

0.680

High

1049723

ARHG7
Rho guanine nucleotide exchange factor 7

3

4

Small-scale

0.680

High

387302

P53
Cellular tumor antigen p53

4

15

Small-scale

0.680

High

1085256

MAR1
Melanoma antigen recognized by T-cells 1

3

1

Small-scale

0.671

High

1273700

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

3

13

Small-scale

0.670

High

1070998

ERBB4
Receptor tyrosine-protein kinase erbB-4

2

20

Small-scale

0.667

High

170560

LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

3

12

High-throughput

0.667

High

946429

EREP3
Protein ENTREP3

3

14

High-throughput

0.667

High

1127378

T255A
Transmembrane protein 255A

3

5

High-throughput

0.667

High

1166753

TMM92
Transmembrane protein 92

3

2

High-throughput

0.667

High

1261330

TM171
Transmembrane protein 171

3

4

High-throughput

0.667

High

808226

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

18

Small-scale

0.665

High

151140

DVL2
Segment polarity protein dishevelled homolog DVL-2

3

20

Small-scale

0.664

High

1115378

TIGIT
T-cell immunoreceptor with Ig and ITIM domains

1

0

High-throughput

0.656

High

1294848

NFIP1
NEDD4 family-interacting protein 1

3

17

Small-scale

0.651

High

1190062

MAVS
Mitochondrial antiviral-signaling protein

3

12

Small-scale

0.650

High

135948

UBE2C
Ubiquitin-conjugating enzyme E2 C

1

20

Small-scale

0.647

High

475140

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

20

Small-scale

0.647

High

896184

UBC12
NEDD8-conjugating enzyme Ubc12

1

20

Small-scale

0.647

High

1174523

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

20

Small-scale

0.647

High

1192659

UB2Q1
Ubiquitin-conjugating enzyme E2 Q1

1

2

Small-scale

0.647

High

1231676

UB2J2
Ubiquitin-conjugating enzyme E2 J2

1

20

Small-scale

0.647

High

1261685

UB2Q2
Ubiquitin-conjugating enzyme E2 Q2

1

2

Small-scale

0.647

High

1282329

UB2E3
Ubiquitin-conjugating enzyme E2 E3

1

20

Small-scale

0.647

High

1294853

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

20

Small-scale

0.647

High

1294879

UVRAG
UV radiation resistance-associated gene protein

1

2

High-throughput

0.647

High

1294888

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

20

Small-scale

0.647

High

402356

JUN
Transcription factor Jun

3

6

Small-scale

0.646

High

1083922

NFE2
Transcription factor NF-E2 45 kDa subunit

2

13

Small-scale

0.643

High

436743

GLI1
Zinc finger protein GLI1

2

4

Small-scale

0.641

High

1119026

AMOT
Angiomotin

3

20

Small-scale

0.640

High

1294851

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

2

7

Small-scale

0.639

High

1039511

LAPM5
Lysosomal-associated transmembrane protein 5

2

7

Small-scale

0.639

High

1043731

ASPP2
Apoptosis-stimulating of p53 protein 2

2

12

Small-scale

0.634

High

131270

BIN1
Myc box-dependent-interacting protein 1

2

7

Small-scale

0.629

High

967940

PO5F1
POU domain, class 5, transcription factor 1

2

4

Small-scale

0.629

High

1197918

ILDR1
Immunoglobulin-like domain-containing receptor 1

2

5

High-throughput

0.628

High

1241904

ARRD4
Arrestin domain-containing protein 4

2

20

Small-scale

0.628

High

338840

EGFR
Epidermal growth factor receptor

2

20

High-throughput

0.624

High

624998

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

10

High-throughput

0.624

High

686035

ARRB2
Beta-arrestin-2

2

4

Small-scale

0.624

High

1270607

STAM1
Signal transducing adapter molecule 1

2

19

Small-scale

0.624

High

1294843

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

2

8

Small-scale

0.624

High

1285838

SGK3
Serine/threonine-protein kinase Sgk3

1

19

Small-scale

0.618

High

125652

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

15

Small-scale

0.618

High

488778

ARAF
Serine/threonine-protein kinase A-Raf

1

16

Small-scale

0.618

High

1287797

HAVR1
Hepatitis A virus cellular receptor 1

1

2

Small-scale

0.618

High

1294869

RASF1
Ras association domain-containing protein 1

1

8

Small-scale

0.618

High

1205013

DTX1
E3 ubiquitin-protein ligase DTX1

2

1

Small-scale

0.611

High

1294871

NFIP2
NEDD4 family-interacting protein 2

2

17

Small-scale

0.611

High

1291858

WBP1
WW domain-binding protein 1

3

10

High-throughput

0.609

High

723192

RORA
Nuclear receptor ROR-alpha

2

12

Small-scale

0.608

High

1294892

SNX9
Sorting nexin-9

1

3

Small-scale

0.604

High

566783

JUNB
Transcription factor JunB

2

8

Small-scale

0.602

High

950248

SMAD3
Mothers against decapentaplegic homolog 3

2

20

Small-scale

0.602

High

1105478

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

6

High-throughput

0.602

High

1294850

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

2

15

High-throughput

0.602

High

1294852

TMG4
Transmembrane gamma-carboxyglutamic acid protein 4

2

14

Small-scale

0.602

High

529568

CFTR
Cystic fibrosis transmembrane conductance regulator

2

4

High-throughput

0.601

High

827260

ARRB1
Beta-arrestin-1

2

4

Small-scale

0.601

High

1201874

TAXB1
Tax1-binding protein 1

2

10

Small-scale

0.601

High

1084871

SMN
Survival motor neuron protein

2

0

Small-scale

0.598

High

254412

N4BP1
NEDD4-binding protein 1

1

2

Small-scale

0.586

High

1054789

CASL
Enhancer of filamentation 1

1

5

Small-scale

0.586

High

1294885

CBLC
E3 ubiquitin-protein ligase CBL-C

1

7

Small-scale

0.586

High

1294842

CGRF1
Cell growth regulator with RING finger domain protein 1

2

0

High-throughput

0.585

High

160143

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

16

Small-scale

0.584

High

201397

M3K7
Mitogen-activated protein kinase kinase kinase 7

2

8

Small-scale

0.584

High

206970

SMAD6
Mothers against decapentaplegic homolog 6

2

20

Small-scale

0.584

High

259303

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

2

4

Small-scale

0.584

High

350454

RASK
GTPase KRas

2

4

High-throughput

0.584

High

610478

CBL
E3 ubiquitin-protein ligase CBL

2

12

Small-scale

0.584

High

962919

MDM2
E3 ubiquitin-protein ligase Mdm2

2

4

Small-scale

0.584

High

1038307

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

2

13

Small-scale

0.584

High

1084139

OCLN
Occludin

2

5

Small-scale

0.584

High

1273604

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

20

Small-scale

0.584

High

800994

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

1

15

Small-scale

0.578

High

1239413

MLKL
Mixed lineage kinase domain-like protein

1

2

Small-scale

0.578

High

1294866

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

Small-scale

0.578

High

1294886

SUFU
Suppressor of fused homolog

1

1

Small-scale

0.578

High

1294846

SH3G3
Endophilin-A3

2

11

High-throughput

0.571

High

1286043

SARAF
Store-operated calcium entry-associated regulatory factor

2

1

High-throughput

0.567

High

215016

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

4

High-throughput

0.561

High

800819

MK08
Mitogen-activated protein kinase 8

1

2

Small-scale

0.561

High

883230

SIK1
Serine/threonine-protein kinase SIK1

1

11

Small-scale

0.561

High

1077929

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

3

Small-scale

0.561

High

1078624

SMAD2
Mothers against decapentaplegic homolog 2

1

20

Small-scale

0.561

High

1233832

MALD2
MARVEL domain-containing protein 2

1

5

Small-scale

0.561

High

1254708

DTX3L
E3 ubiquitin-protein ligase DTX3L

1

1

Small-scale

0.561

High

1294849

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

1

2

Small-scale

0.561

High

126954

WASL
Actin nucleation-promoting factor WASL

1

9

High-throughput

0.541

High

152190

TMG1
Transmembrane gamma-carboxyglutamic acid protein 1

1

14

High-throughput

0.536

High

253908

LRP3
Low-density lipoprotein receptor-related protein 3

1

18

High-throughput

0.536

High

429103

ADRB2
Beta-2 adrenergic receptor

1

3

Small-scale

0.536

High

725523

COPB2
Coatomer subunit beta'

1

7

High-throughput

0.536

High

813676

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.536

High

904987

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

1042286

CUL3
Cullin-3

1

5

High-throughput

0.536

High

1125754

ARSH
Arylsulfatase H

1

1

High-throughput

0.536

High

1252807

ARRD2
Arrestin domain-containing protein 2

1

20

High-throughput

0.536

High

1294868

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.536

High

1294870

TNR19
Tumor necrosis factor receptor superfamily member 19

1

3

High-throughput

0.536

High

869511

ATN1
Atrophin-1

1

9

Small-scale

0.527

High

684266

1433S
14-3-3 protein sigma

1

20

High-throughput

0.515

High

1072159

PCBP2
Poly(rC)-binding protein 2

1

14

Small-scale

0.515

High

1273570

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

17

High-throughput

0.515

High

1294839

SNX18
Sorting nexin-18

1

3

Small-scale

0.515

High

1294860

FXL15
F-box/LRR-repeat protein 15

1

10

Small-scale

0.515

High

1263767

JPH3
Junctophilin-3

1

5

High-throughput

0.515

High

1243026

GLIS3
Zinc finger protein GLIS3

1

4

Small-scale

0.512

High

146268

ARI1A
AT-rich interactive domain-containing protein 1A

1

13

High-throughput

0.501

High

200183

TGFI1
Transforming growth factor beta-1-induced transcript 1 protein

1

9

High-throughput

0.501

High

277114

STAM2
Signal transducing adapter molecule 2

1

20

Small-scale

0.501

High

295656

RMP
Unconventional prefoldin RPB5 interactor 1

1

3

High-throughput

0.501

High

348866

RASN
GTPase NRas

1

4

Small-scale

0.501

High

391445

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

1

Small-scale

0.501

High

503297

MTAP2
Microtubule-associated protein 2

1

12

High-throughput

0.501

High

516643

PABP1
Polyadenylate-binding protein 1

1

7

High-throughput

0.501

High

541109

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

8

High-throughput

0.501

High

568765

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

18

Small-scale

0.501

High

583549

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

8

High-throughput

0.501

High

583768

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

3

High-throughput

0.501

High

632856

TYY1
Transcriptional repressor protein YY1

1

4

High-throughput

0.501

High

647191

1433T
14-3-3 protein theta

1

20

Small-scale

0.501

High

676969

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

8

High-throughput

0.501

High

739603

SCNNA
Amiloride-sensitive sodium channel subunit alpha

1

20

Small-scale

0.501

High

845977

SCNNB
Amiloride-sensitive sodium channel subunit beta

1

20

Small-scale

0.501

High

934396

CSK21
Casein kinase II subunit alpha

1

7

Small-scale

0.501

High

967360

EWS
RNA-binding protein EWS

1

4

High-throughput

0.501

High

972238

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

16

Small-scale

0.501

High

1049868

UBP2L
Ubiquitin-associated protein 2-like

1

10

High-throughput

0.501

High

1060871

IMB1
Importin subunit beta-1

1

7

Small-scale

0.501

High

1075726

SF01
Splicing factor 1

1

3

High-throughput

0.501

High

1134134

UBAP2
Ubiquitin-associated protein 2

1

10

High-throughput

0.501

High

1162371

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

2

High-throughput

0.501

High

1217973

KSR1
Kinase suppressor of Ras 1

1

17

Small-scale

0.501

High

1221346

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

3

High-throughput

0.501

High

1233663

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

4

High-throughput

0.501

High

1235773

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

11

High-throughput

0.501

High

1235881

MYCT1
Myc target protein 1

1

1

High-throughput

0.501

High

1251602

SMRC2
SWI/SNF complex subunit SMARCC2

1

12

High-throughput

0.501

High

1272920

SMRC1
SWI/SNF complex subunit SMARCC1

1

9

High-throughput

0.501

High

1281223

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

7

High-throughput

0.501

High

1290129

DAZP1
DAZ-associated protein 1

1

15

High-throughput

0.501

High

1294836

RBM14
RNA-binding protein 14

1

8

High-throughput

0.501

High

1294838

TREF1
Transcriptional-regulating factor 1

1

5

High-throughput

0.501

High

1294841

MINT
Msx2-interacting protein

1

8

High-throughput

0.501

High

1294854

TTYH3
Protein tweety homolog 3

1

2

High-throughput

0.501

High

1294863

RPAP3
RNA polymerase II-associated protein 3

1

14

High-throughput

0.501

High

1294884

STRP2
Striatin-interacting protein 2

1

1

High-throughput

0.501

High

1294887

M3K2
Mitogen-activated protein kinase kinase kinase 2

1

11

High-throughput

0.501

High

1294873

CUED1
CUE domain-containing protein 1

1

6

High-throughput

0.489

High

1054187

BECN1
Beclin-1

1

1

Small-scale

0.481

High

48128

UBA6
Ubiquitin-like modifier-activating enzyme 6

1

4

High-throughput

0.479

High

64219

UBP27
Ubiquitin carboxyl-terminal hydrolase 27

1

5

Small-scale

0.479

High

120584

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

127039

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

5

High-throughput

0.479

High

150747

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

20

Small-scale

0.479

High

154403

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

3

Small-scale

0.479

High

156547

SCAM3
Secretory carrier-associated membrane protein 3

1

3

High-throughput

0.479

High

158526

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

13

Small-scale

0.479

High

165870

KDM6B
Lysine-specific demethylase 6B

1

7

Small-scale

0.479

High

200938

MTSS1
Protein MTSS 1

1

13

Small-scale

0.479

High

230164

MGRN1
E3 ubiquitin-protein ligase MGRN1

1

1

Small-scale

0.479

High

347601

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.479

High

375773

GBA1
Lysosomal acid glucosylceramidase

1

1

Small-scale

0.479

High

436457

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

437444

4F2
Amino acid transporter heavy chain SLC3A2

1

4

High-throughput

0.479

High

441768

CFAH
Complement factor H

1

4

Small-scale

0.479

High

504580

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

517408

PCNA
Proliferating cell nuclear antigen

1

3

High-throughput

0.479

High

526020

IFM1
Interferon-induced transmembrane protein 1

1

3

High-throughput

0.479

High

545560

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

553446

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

564644

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

584457

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

7

Small-scale

0.479

High

599713

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

6

Small-scale

0.479

High

601974

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

Small-scale

0.479

High

607135

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

4

High-throughput

0.479

High

651966

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

719065

PHB1
Prohibitin 1

1

6

High-throughput

0.479

High

721167

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

738569

TGFR1
TGF-beta receptor type-1

1

19

Small-scale

0.479

High

791868

HD
Huntingtin

1

4

Small-scale

0.479

High

800615

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

1

20

High-throughput

0.479

High

804318

NOTC1
Neurogenic locus notch homolog protein 1

1

13

Small-scale

0.479

High

818354

SOX2
Transcription factor SOX-2

1

7

High-throughput

0.479

High

845166

RAB7A
Ras-related protein Rab-7a

1

2

High-throughput

0.479

High

845668

RAB9A
Ras-related protein Rab-9A

1

2

High-throughput

0.479

High

852587

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

853426

IMA1
Importin subunit alpha-1

1

6

High-throughput

0.479

High

868298

ATX3
Ataxin-3

1

4

Small-scale

0.479

High

879541

BID
BH3-interacting domain death agonist

1

1

Small-scale

0.479

High

892540

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

894313

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

900802

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

915895

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

925520

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

944125

JAG1
Protein jagged-1

1

9

Small-scale

0.479

High

951237

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

965797

IFM3
Interferon-induced transmembrane protein 3

1

3

High-throughput

0.479

High

974975

CAV1
Caveolin-1

1

2

Small-scale

0.479

High

992033

BAX
Apoptosis regulator BAX

1

3

Small-scale

0.479

High

1027416

STK3
Serine/threonine-protein kinase 3

1

19

Small-scale

0.479

High

1035547

SMAD4
Mothers against decapentaplegic homolog 4

1

20

High-throughput

0.479

High

1044412

PTC1
Protein patched homolog 1

1

13

Small-scale

0.479

High

1076704

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

1078134

AAAT
Neutral amino acid transporter B(0)

1

1

High-throughput

0.479

High

1078535

NCOA1
Nuclear receptor coactivator 1

1

2

Small-scale

0.479

High

1130453

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

10

High-throughput

0.479

High

1132451

MARH8
E3 ubiquitin-protein ligase MARCHF8

1

3

High-throughput

0.479

High

1138853

OTU1
Ubiquitin thioesterase OTU1

1

1

Small-scale

0.479

High

1152436

GRAM4
GRAM domain-containing protein 4

1

1

Small-scale

0.479

High

1165858

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

1171253

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1183506

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1188717

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

1199316

MARH3
E3 ubiquitin-protein ligase MARCHF3

1

3

High-throughput

0.479

High

1205571

LRAD3
Low-density lipoprotein receptor class A domain-containing protein 3

1

6

Small-scale

0.479

High

1223858

AN13A
Ankyrin repeat domain-containing protein 13A

1

10

Small-scale

0.479

High

1240725

RN149
E3 ubiquitin-protein ligase RNF149

1

5

High-throughput

0.479

High

1245132

TNIP2
TNFAIP3-interacting protein 2

1

3

High-throughput

0.479

High

1251227

WDR48
WD repeat-containing protein 48

1

4

Small-scale

0.479

High

1255979

RN128
E3 ubiquitin-protein ligase RNF128

1

4

High-throughput

0.479

High

1260379

PDC6I
Programmed cell death 6-interacting protein

1

10

High-throughput

0.479

High

1269203

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

1287337

OPTN
Optineurin

1

17

High-throughput

0.479

High

1294840

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

1

High-throughput

0.479

High

1294847

PD1L2
Programmed cell death 1 ligand 2

1

6

Small-scale

0.479

High

1294859

DNJC5
DnaJ homolog subfamily C member 5

1

2

High-throughput

0.479

High

1294861

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1294862

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.479

High

1294864

TRPV4
Transient receptor potential cation channel subfamily V member 4

1

2

Small-scale

0.479

High

1294865

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1294867

ANLN
Anillin

1

1

High-throughput

0.479

High

1294875

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.479

High

1294876

GGA3
ADP-ribosylation factor-binding protein GGA3

1

16

Small-scale

0.479

High

1294880

HDAC6
Histone deacetylase 6

1

4

High-throughput

0.479

High

1294881

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1294882

DDX20
Probable ATP-dependent RNA helicase DDX20

1

13

Small-scale

0.479

High

1294889

SHLB1
Endophilin-B1

1

9

Small-scale

0.479

High

1294891

TRAF6
TNF receptor-associated factor 6

1

20

Small-scale

0.479

High

1294893

NEMO
NF-kappa-B essential modulator

1

9

Small-scale

0.479

High

214347

SPOP
Speckle-type POZ protein

1

0

Small-scale

0.458

High

270320

LRP6
Low-density lipoprotein receptor-related protein 6

1

0

Small-scale

0.458

High

414034

GELS
Gelsolin

1

0

Small-scale

0.458

High

760555

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

0

High-throughput

0.458

High

1152035

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1283031

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.458

High

1294837

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

Small-scale

0.458

High

1294874

GEMI8
Gem-associated protein 8

1

0

Small-scale

0.458

High

267435

ECI2
Enoyl-CoA delta isomerase 2

1

5

High-throughput

0.445

High

740040

TGFR2
TGF-beta receptor type-2

1

19

High-throughput

0.445

High

994672

DDR1
Epithelial discoidin domain-containing receptor 1

1

14

Small-scale

0.445

High

1022579

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

6

High-throughput

0.445

High

1145882

CP135
Centrosomal protein of 135 kDa

1

9

High-throughput

0.445

High

164449

TRI66
Tripartite motif-containing protein 66

1

8

High-throughput

0.437

High

1024875

KLF10
Krueppel-like factor 10

1

6

Small-scale

0.437

High

1159413

FBX42
F-box only protein 42

1

4

Small-scale

0.437

High

886320

DSCR9
Down syndrome critical region protein 9

1

1

High-throughput

0.417

High

567219

CXA1
Gap junction alpha-1 protein

1

2

High-throughput

0.408

High

1244785

REPS2
RalBP1-associated Eps domain-containing protein 2

1

4

High-throughput

0.408

High

1256023

RHBL4
Rhomboid-related protein 4

1

2

High-throughput

0.408

High

1294844

SH3G1
Endophilin-A2

1

10

Small-scale

0.408

High

1288148

ESS2
Splicing factor ESS-2 homolog

1

1

High-throughput

0.373

High

1294883

K1210
Acrosomal protein KIAA1210

1

0

High-throughput

0.261

Low

1287262

PKHB2
Pleckstrin homology domain-containing family B member 2

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024