HitPredict

Interactor 1: FXR2 (P51116)
RNA-binding protein FXR2 (FXR2P) (FMR1 autosomal homolog 2)
Gene: FXR2

Interactor 2: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0017148 - negative regulation of translation
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 673 Hs			1 391
+	Hs
		586625 FXR2_HUMAN (1-673): 0: 1004: 100.00		CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08
+	Mm
		1142916 FXR1_MOUSE (14-673): 0: 981: 62.83		GSK3B_MOUSE (39-389): 4.72e-112: 335: 29.12
+	Hs
		843607 FXR1_HUMAN (14-673): 0: 798: 51.34		CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00
+	Hs
		835593 FXR1_HUMAN (14-673): 0: 798: 51.34		GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12
+	Mm
		1141312 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		CSK21_MOUSE (1-391): 4.08e-134: 390: 98.72
+	Mm
		222424 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		CSK22_MOUSE (1-334): 4.23e-119: 351: 85.08
+	Mm
		1207113 Q8BPK8_MOUSE (14-344): 0: 621: 71.90		GSK3B_MOUSE (39-389): 4.72e-112: 335: 29.12
+	Mm
		729481 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		CSK21_MOUSE (1-391): 4.08e-134: 390: 98.72
+	Mm
		222415 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		CSK22_MOUSE (1-334): 4.23e-119: 351: 85.08
+	Mm
		729609 FMR1_MOUSE (229-475): 4.6e-46: 174: 34.20		GSK3B_MOUSE (39-389): 4.72e-112: 335: 29.12