Protein: UTP6
U3 small nucleolar RNA-associated protein 6 homolog (Hepatocellular carcinoma-associated antigen 66) (Multiple hat domains protein)

Gene: UTP6
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q9NYH9

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
GO:0005730 - nucleolus
GO:0030515 - snoRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1161717

IF16
Gamma-interferon-inducible protein 16

2

5

High-throughput

0.611

High

1399447

WDFY2
WD repeat and FYVE domain-containing protein 2

3

9

High-throughput

0.609

High

665057

IL4RA
Interleukin-4 receptor subunit alpha

2

0

High-throughput

0.602

High

1447352

ANLN
Anillin

2

4

High-throughput

0.584

High

1402869

GPX7
Glutathione peroxidase 7

2

1

High-throughput

0.574

High

854350

KI67
Proliferation marker protein Ki-67

1

2

High-throughput

0.536

High

1144191

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

1404463

CDC5L
Cell division cycle 5-like protein

1

11

High-throughput

0.515

High

167408

KLF11
Krueppel-like factor 11

1

4

High-throughput

0.515

High

844037

HD
Huntingtin

1

2

High-throughput

0.515

High

388318

GLPA
Glycophorin-A

1

0

High-throughput

0.513

High

832818

BCL6
B-cell lymphoma 6 protein

1

0

Small-scale

0.513

High

1332117

EIF1A
Probable RNA-binding protein EIF1AD

1

0

High-throughput

0.513

High

1410993

RHXF2
Rhox homeobox family member 2

1

2

High-throughput

0.494

High

74627

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

14

High-throughput

0.489

High

294433

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.489

High

445273

S10A6
Protein S100-A6

1

1

High-throughput

0.489

High

718477

CD6
T-cell differentiation antigen CD6

1

2

High-throughput

0.489

High

1091360

FOXL1
Forkhead box protein L1

1

2

High-throughput

0.489

High

1248447

LRSM1
E3 ubiquitin-protein ligase LRSAM1

1

1

High-throughput

0.489

High

1316307

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

1

High-throughput

0.489

High

1331613

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

5

High-throughput

0.489

High

1359395

DNJB3
DnaJ homolog subfamily B member 3

1

2

High-throughput

0.489

High

1387281

HDA11
Histone deacetylase 11

1

4

High-throughput

0.489

High

1402724

TCPQM
T-complex protein 1 subunit theta-like 2

1

2

High-throughput

0.489

High

1452603

TFP11
Tuftelin-interacting protein 11

1

6

High-throughput

0.481

High

129492

MEN1
Menin

1

5

High-throughput

0.479

High

170386

AURKA
Aurora kinase A

1

1

High-throughput

0.479

High

173467

XPO1
Exportin-1

1

3

High-throughput

0.479

High

223382

PRC1
Protein regulator of cytokinesis 1

1

2

High-throughput

0.479

High

248114

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

373327

MYC
Myc proto-oncogene protein

1

9

High-throughput

0.479

High

404480

GCR
Glucocorticoid receptor

1

13

High-throughput

0.479

High

447517

NPM
Nucleophosmin

1

4

High-throughput

0.479

High

589877

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

696696

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

769355

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.479

High

854947

RECQ1
ATP-dependent DNA helicase Q1

1

3

High-throughput

0.479

High

872814

SOX2
Transcription factor SOX-2

1

6

High-throughput

0.479

High

879542

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

5

High-throughput

0.479

High

1100463

TIF1B
Transcription intermediary factor 1-beta

1

6

High-throughput

0.479

High

1107279

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

1341156

WDR36
WD repeat-containing protein 36

1

12

Small-scale

0.479

High

1346958

SNIP1
Smad nuclear-interacting protein 1

1

3

High-throughput

0.479

High

1404805

RING2
E3 ubiquitin-protein ligase RING2

1

8

High-throughput

0.479

High

1448214

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.479

High

1452242

AATF
Protein AATF

1

2

High-throughput

0.479

High

1452602

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

1

High-throughput

0.479

High

642592

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

2

High-throughput

0.470

High

384738

CRYAB
Alpha-crystallin B chain

1

4

High-throughput

0.445

High

541062

PIM1
Serine/threonine-protein kinase pim-1

1

1

High-throughput

0.445

High

1006760

SRPK2
SRSF protein kinase 2

1

8

High-throughput

0.445

High

1130495

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

4

High-throughput

0.445

High

1391809

AURKB
Aurora kinase B

1

1

High-throughput

0.445

High

1452610

NOC2L
Nucleolar complex protein 2 homolog

1

1

High-throughput

0.445

High

1179939

TXIP1
Translin-associated factor X-interacting protein 1

1

1

High-throughput

0.439

High

1387412

ESS2
Splicing factor ESS-2 homolog

1

2

High-throughput

0.439

High

1400086

QKI
KH domain-containing RNA-binding protein QKI

1

4

High-throughput

0.439

High

1452608

TRAK1
Trafficking kinesin-binding protein 1

1

9

High-throughput

0.439

High

157929

CTRO
Citron Rho-interacting kinase

1

5

High-throughput

0.437

High

272509

OBSL1
Obscurin-like protein 1

1

4

High-throughput

0.437

High

346422

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

9

High-throughput

0.437

High

942925

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

3

High-throughput

0.437

High

1140948

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.437

High

1249268

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

1255836

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

1276877

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

6

High-throughput

0.437

High

1431327

ATG5
Autophagy protein 5

1

1

High-throughput

0.437

High

1433543

RHOJ
Rho-related GTP-binding protein RhoJ

1

2

High-throughput

0.437

High

1434069

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.437

High

1452605

XPO7
Exportin-7

1

3

High-throughput

0.437

High

1452607

HECD1
E3 ubiquitin-protein ligase HECTD1

1

4

High-throughput

0.437

High

679407

DNJB2
DnaJ homolog subfamily B member 2

1

2

High-throughput

0.407

High

1181442

P3H1
Prolyl 3-hydroxylase 1

1

1

High-throughput

0.407

High

1334421

UXS1
UDP-glucuronic acid decarboxylase 1

1

1

High-throughput

0.407

High

1390922

LRC46
Leucine-rich repeat-containing protein 46

1

4

High-throughput

0.407

High

622694

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

0

High-throughput

0.328

High

1204718

TAF7L
Transcription initiation factor TFIID subunit 7-like

2

0

High-throughput

0.328

High

1438630

GPBL1
Vasculin-like protein 1

2

0

High-throughput

0.328

High

736899

GBP1
Guanylate-binding protein 1

2

0

High-throughput

0.324

High

1154603

CC85B
Coiled-coil domain-containing protein 85B

1

0

High-throughput

0.282

High

1410537

KXDL1
KxDL motif-containing protein 1

1

0

High-throughput

0.282

High

192137

PA2GX
Group 10 secretory phospholipase A2

1

0

High-throughput

0.279

Low

280963

HYPM
Huntingtin-interacting protein M

1

0

High-throughput

0.279

Low

1158831

CART

1

0

High-throughput

0.279

Low

1369501

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.279

Low

1420239

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.279

Low

1452604

GHRL
Appetite-regulating hormone

1

0

High-throughput

0.279

Low

1452611

GPSM3
G-protein-signaling modulator 3

1

0

High-throughput

0.279

Low

1400679

RHG07
Rho GTPase-activating protein 7

1

0

High-throughput

0.269

Low

387473

APOE
Apolipoprotein E

1

0

High-throughput

0.268

Low

642305

COMT
Catechol O-methyltransferase

1

0

High-throughput

0.268

Low

593005

ACADS
Short-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

1418961

WNK3
Serine/threonine-protein kinase WNK3

1

0

High-throughput

0.249

Low

1452427

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

0

High-throughput

0.249

Low

231644

PRKY
Putative serine/threonine-protein kinase PRKY

1

0

High-throughput

0.232

Low

457744

TBB5
Tubulin beta chain

1

0

High-throughput

0.232

Low

561392

TDGF1
Protein Cripto

1

0

High-throughput

0.232

Low

1091911

NPRL3
GATOR1 complex protein NPRL3

1

0

High-throughput

0.232

Low

1153489

EFNB3
Ephrin-B3

1

0

High-throughput

0.232

Low

1382704

EMID1
EMI domain-containing protein 1

1

0

High-throughput

0.232

Low

1412966

FUZZY
Protein fuzzy homolog

1

0

High-throughput

0.232

Low

1452606

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

0

High-throughput

0.232

Low

1452609

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025