HitPredict

Interactor 1: GRAM (P51124)
Granzyme M (EC 3.4.21.-) (Met-1 serine protease) (Hu-Met-1) (Met-ase) (Natural killer cell granular protease)
Gene: GZMM

Interactor 2: TBA4A (P68366)
Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain)
Gene: TUBA4A

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	18523284
Identification Methods	protease assay
Interaction Type	protein cleavage

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 257 Hs			1 448
+	Hs
		844335 GRAM_HUMAN (1-257): 1.22e-107: 313: 100.00		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		1309494 TMPS5_HUMAN (10-256): 4.51e-99: 298: 32.69		TBA1C_HUMAN (1-448): 0: 726: 96.21
+	Hs
		714751 TRY3_HUMAN (12-257): 1.2e-104: 307: 32.80		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		933614 TMPS5_HUMAN (10-256): 4.51e-99: 298: 32.69		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		1309527 KLK11_HUMAN (23-256): 5.44e-98: 289: 34.03		TBA1C_HUMAN (1-448): 0: 726: 96.21
+	Hs
		933653 KLK11_HUMAN (23-256): 5.44e-98: 289: 34.03		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		1175177 TMPS5_HUMAN (10-256): 4.51e-99: 298: 32.69		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		933554 KLK6_HUMAN (5-255): 1.94e-97: 286: 31.50		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		933221 PRSS8_HUMAN (14-253): 7.09e-98: 291: 29.41		TBA1B_HUMAN (1-439): 0: 715: 97.49
+	Hs
		1175223 KLK11_HUMAN (23-256): 5.44e-98: 289: 34.03		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		428427 TMPS5_HUMAN (10-256): 4.51e-99: 298: 32.69		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		933971 TMPS5_HUMAN (10-256): 4.51e-99: 298: 32.69		TBB4B_HUMAN (1-437): 0: 695: 40.28
+	Mm
		371482 CFAD_MOUSE (1-253): 1.38e-49: 165: 35.66		TBA1B_MOUSE (1-439): 0: 715: 97.49
+	Mm
		371765 CFAD_MOUSE (1-253): 1.38e-49: 165: 35.66		TBB4B_MOUSE (1-437): 0: 695: 40.28
+	Hs
		595562 GRAH_HUMAN (25-255): 9.48e-38: 134: 38.24		TBA1C_HUMAN (1-448): 0: 726: 96.21
+	Hs
		595527 GRAH_HUMAN (25-255): 9.48e-38: 134: 38.24		TBA4A_HUMAN (1-448): 0: 724: 100.00
+	Hs
		486167 GRAB_HUMAN (25-255): 4.24e-39: 137: 36.82		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		595544 GRAH_HUMAN (25-255): 9.48e-38: 134: 38.24		TBA1A_HUMAN (1-439): 0: 712: 97.04
+	Hs
		428017 GRAH_HUMAN (25-255): 9.48e-38: 134: 38.24		TBB5_HUMAN (1-439): 0: 697: 40.55
+	Hs
		428023 PRTN3_HUMAN (25-255): 1.19e-33: 124: 37.24		TBB5_HUMAN (1-439): 0: 697: 40.55