HitPredict

Interactor 1: DVL1 (P51141)
Segment polarity protein dishevelled homolog DVL-1 (Dishevelled-1) (DSH homolog 1)
Gene: DVL1

Interactor 2: DACT3 (Q0PHV7)
Dapper homolog 3 (Dapper antagonist of catenin 3)
Gene: DACT3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21718540
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0060070 - canonical Wnt signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 695 Mm			1 610
+	Mm
		844426 DVL1_MOUSE (1-695): 0: 602: 100.00		DACT2_MOUSE (8-610): 3.07e-110: 349: 24.02
+	Rn
		88714 DVL1_RAT (1-695): 0: 604: 99.57		D3ZSK6_RAT (8-610): 1.25e-95: 311: 22.87
+	Mm
		1012048 DVL3_MOUSE (1-695): 7.49e-164: 490: 60.83		DACT3_MOUSE (1-610): 1.33e-119: 369: 100.00
+	Mm
		1142089 DVL3_MOUSE (1-695): 7.49e-164: 490: 60.83		DACT2_MOUSE (8-610): 3.07e-110: 349: 24.02
+	Mm
		1012047 DVL2_MOUSE (3-695): 3.84e-152: 460: 58.29		DACT3_MOUSE (1-610): 1.33e-119: 369: 100.00
+	Mm
		1141499 DVL2_MOUSE (3-695): 3.84e-152: 460: 58.29		DACT2_MOUSE (8-610): 3.07e-110: 349: 24.02
+	Rn
		88704 D4ADV8_RAT (1-691): 5.8e-159: 477: 60.34		D3ZSK6_RAT (8-610): 1.25e-95: 311: 22.87
+	Mm
		844430 DVL1_MOUSE (1-695): 0: 602: 100.00		DACT1_MOUSE (9-497): 7.46e-43: 166: 18.39
+	Rn
		88914 DVL1_RAT (1-695): 0: 604: 99.57		D4A3W8_RAT (9-449): 7.95e-42: 163: 17.80
+	Rn
		88525 D3ZB71_RAT (3-695): 1.73e-148: 451: 58.42		D3ZSK6_RAT (8-610): 1.25e-95: 311: 22.87
+	Mm
		1142091 DVL3_MOUSE (1-695): 7.49e-164: 490: 60.83		DACT1_MOUSE (9-497): 7.46e-43: 166: 18.39
+	Xl
		844441 DVL2_XENLA (1-695): 1.19e-152: 461: 54.08		DCT1B_XENLA (9-227): 4.53e-50: 187: 27.43
+	Rn
		88909 D4ADV8_RAT (1-691): 5.8e-159: 477: 60.34		D4A3W8_RAT (9-449): 7.95e-42: 163: 17.80
+	Dr
		1163513 Q803Q5_DANRE (1-695): 7.89e-158: 475: 53.21		DACT1_DANRE (12-395): 5.5e-41: 161: 19.46
+	Mm
		1141504 DVL2_MOUSE (3-695): 3.84e-152: 460: 58.29		DACT1_MOUSE (9-497): 7.46e-43: 166: 18.39
+	Rn
		88526 D3ZB71_RAT (3-695): 1.73e-148: 451: 58.42		D4A3W8_RAT (9-449): 7.95e-42: 163: 17.80
+	Hs
		151222 DVL2_HUMAN (3-695): 2.79e-147: 448: 57.75		DACT1_HUMAN (9-428): 4.31e-37: 149: 18.97
+	Hs
		151078 DVL2_HUMAN (3-695): 2.79e-147: 448: 57.75		CORA1_HUMAN (98-463): 6.63e-09: 61.2: 16.94
+	Mm
		88462 NEB2_MOUSE (58-423): 9.67e-47: 179: 15.41		D3Z656_MOUSE (92-562): 1.21e-10: 67: 13.10
+	Mm
		1164093 NEB2_MOUSE (58-423): 9.67e-47: 179: 15.41		PCLO_MOUSE (134-511): 5.43e-10: 65.1: 9.92