HitPredict

Interactor 1: RAB5C (P51148)
Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
Gene: RAB5C

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane GO:0005811 - lipid droplet GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 216 Hs			1 1164
+	Hs
		592410 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		TSC1_HUMAN (1-1164): 0: 725: 100.00
+	Hs
		914256 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		TSC1_HUMAN (1-1164): 0: 725: 100.00
+	Hs
		1079935 RB11B_HUMAN (12-216): 8.62e-85: 252: 38.89		Q86WV8_HUMAN (1-343): 3.4e-177: 526: 100.00
+	Dm
		1001875 RAB5_DROME (2-214): 2.73e-99: 288: 74.65		Q0KI67_DROME (441-1011): 8.87e-23: 107: 11.72
+	Hs
		592661 RAB6A_HUMAN (16-213): 2.31e-51: 166: 40.59		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		148636 RAB1A_HUMAN (12-214): 1.9e-93: 273: 41.18		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		149274 RAB1B_HUMAN (14-214): 1.47e-90: 265: 40.30		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		148389 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		254466 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		ROCK2_HUMAN (415-1038): 1.55e-24: 113: 11.27
+	Dm
		115260 RAB5_DROME (2-214): 2.73e-99: 288: 74.65		M9PEK6_DROME (724-1008): 1.41e-09: 64.8: 16.29
+	Hs
		914124 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		MRCKA_HUMAN (278-842): 4.78e-17: 89.1: 8.78
+	Hs
		592236 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		ROCK1_HUMAN (433-926): 6.18e-15: 82.2: 12.00
+	Hs
		592298 RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57		CYTSB_HUMAN (740-1117): 1.86e-12: 74.1: 12.41
+	Hs
		914116 RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25		CYTSB_HUMAN (740-1117): 1.86e-12: 74.1: 12.41
+	Dm
		185599 RAB6_DROME (16-212): 3.61e-51: 166: 41.12		Q0KI67_DROME (441-1011): 8.87e-23: 107: 11.72
+	Dm
		185621 RAB6_DROME (16-212): 3.61e-51: 166: 41.12		MYSN_DROME (417-1038): 2.47e-19: 96.8: 9.88