HitPredict

Interactor 1: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Interactor 2: CHM4B (Q9H444)
Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) (SNF7 homolog associated with Alix 1) (SNF7-2) (hSnf7-2) (Vacuolar protein sorting-associated protein 32-2) (Vps32-2) (hVps32-2)
Gene: CHMP4B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 31586073
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000421 - autophagosome membrane GO:0005765 - lysosomal membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0015031 - protein transport and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 207 Hs			1 224
+	Hs
		1328142 RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		914246 RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99		CHMP7_HUMAN (8-215): 5.6e-42: 149: 21.91
+	Hs
		845634 RAB9A_HUMAN (5-177): 3.51e-68: 209: 56.65		CHMP7_HUMAN (8-215): 5.6e-42: 149: 21.91
+	Hs
		844735 RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		844680 RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		844649 RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44		CHMP7_HUMAN (8-215): 5.6e-42: 149: 21.91