HitPredict

Interactor 1: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Interactor 2: PRAF1 (Q9UI14)
Prenylated Rab acceptor protein 1 (PRA1 family protein 1)
Gene: RABAC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29360040, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 207 Hs			1 185
+	Hs
		918963 RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50		PRAF1_HUMAN (1-185): 5.38e-67: 204: 100.00
+	Hs
		1328155 RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15		PRAF1_HUMAN (1-185): 5.38e-67: 204: 100.00
+	Rn
		192720 RAB1A_RAT (1-206): 7.27e-87: 256: 33.50		PRAF1_RAT (1-185): 2.6e-66: 202: 95.14
+	Hs
		845795 RAB9A_HUMAN (5-177): 3.51e-68: 209: 56.65		PRAF1_HUMAN (1-185): 5.38e-67: 204: 100.00
+	At
		285946 RAE1C_ARATH (4-207): 3.25e-78: 235: 33.01		PR1B4_ARATH (27-181): 6.01e-54: 172: 24.36
+	At
		1338115 RABD1_ARATH (1-206): 8.94e-81: 240: 31.25		PR1F4_ARATH (17-182): 3.68e-52: 166: 18.68
+	At
		1340495 RABD1_ARATH (1-206): 8.94e-81: 240: 31.25		PR1B6_ARATH (33-184): 5.4e-47: 154: 26.14
+	At
		1352357 RABD1_ARATH (1-206): 8.94e-81: 240: 31.25		PR1B2_ARATH (41-181): 1.39e-46: 153: 24.65
+	At
		656921 RAE1C_ARATH (4-207): 3.25e-78: 235: 33.01		PR1F3_ARATH (17-182): 6.85e-48: 156: 18.07
+	At
		656922 RAE1C_ARATH (4-207): 3.25e-78: 235: 33.01		PR1B6_ARATH (33-184): 5.4e-47: 154: 26.14
+	At
		189209 RAE1A_ARATH (4-207): 4.26e-78: 234: 32.06		PR1B2_ARATH (41-181): 1.39e-46: 153: 24.65
+	Hs
		277671 RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00		PRAF3_HUMAN (39-185): 1.57e-39: 134: 21.85
+	Hs
		242240 RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50		PRAF2_HUMAN (36-185): 8.79e-32: 114: 20.13
+	Sc
		350904 YPT1_YEAST (1-206): 8.02e-81: 241: 31.91		PRA1_YEAST (16-179): 9.48e-35: 122: 25.30
+	Hs
		844785 RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44		PRAF1_HUMAN (1-185): 5.38e-67: 204: 100.00
+	At
		221740 RAA1E_ARATH (8-169): 7.18e-37: 129: 40.61		PR1F3_ARATH (17-182): 6.85e-48: 156: 18.07
+	Hs
		277670 RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44		PRAF3_HUMAN (39-185): 1.57e-39: 134: 21.85
+	Hs
		242233 RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44		PRAF2_HUMAN (36-185): 8.79e-32: 114: 20.13