HitPredict

Interactor 1: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Interactor 2: PKHM1 (Q9Y4G2)
Pleckstrin homology domain-containing family M member 1 (PH domain-containing family M member 1) (162 kDa adapter protein) (AP162)
Gene: PLEKHM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.926

The method score is based on:

Property Details
Experiments 27777970, 28325809, 34432599, 33452816, 27291868
Identification Methods affinity chromatography technology, pull down, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ras~zf-RING_9, RUN~Ras
Common GO terms GO:0005764 - lysosome
GO:0015031 - protein transport
GO:0031902 - late endosome membrane
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 207
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024