Interactor 1: DCC (P43146)
Netrin receptor DCC (Colorectal cancer suppressor) (Immunoglobulin superfamily DCC subclass member 1) (Tumor suppressor protein DCC)
Gene: DCC
Interactor 2: SIAH1 (Q8IUQ4)
E3 ubiquitin-protein ligase SIAH1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH1) (Seven in absentia homolog 1) (Siah-1) (Siah-1a)
Gene: SIAH1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 0.60 | 0.586 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9858595, unassigned1973 |
| Identification Methods | pull down, two hybrid fragment pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0007411 - axon guidance |
| Homologous interactions | 1 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
