Protein: DCC
Netrin receptor DCC (Colorectal cancer suppressor) (Immunoglobulin superfamily DCC subclass member 1) (Tumor suppressor protein DCC)

Gene: DCC
Organism: Homo sapiens
Interactions: 72
UniProt ID: P43146

Gene Ontology (top 5):
GO:0001764 - neuron migration
GO:0004888 - transmembrane signaling receptor activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

340701

NET1
Netrin-1

5

13

Small-scale

0.922

High

845972

FAK1
Focal adhesion kinase 1

3

18

Small-scale

0.874

High

691660

MK03
Mitogen-activated protein kinase 3

2

3

Small-scale

0.754

High

519816

ANDR
Androgen receptor

1

5

Small-scale

0.740

High

635689

RASA1
Ras GTPase-activating protein 1

1

6

High-throughput

0.698

High

703479

MK01
Mitogen-activated protein kinase 1

1

3

Small-scale

0.691

High

845991

TRIM9
E3 ubiquitin-protein ligase TRIM9

2

17

Small-scale

0.675

High

845985

CNO6L
CCR4-NOT transcription complex subunit 6-like

1

0

High-throughput

0.656

High

845993

NET4
Netrin-4

1

12

Small-scale

0.647

High

845955

RL5
Large ribosomal subunit protein uL18

2

1

Small-scale

0.646

High

845960

CASP9
Caspase-9

3

1

Small-scale

0.640

High

845982

COR2A
Coronin-2A

1

1

High-throughput

0.625

High

845956

RL28
Large ribosomal subunit protein eL28

2

1

Small-scale

0.621

High

593937

NCK1
SH2/SH3 adapter protein NCK1

1

13

Small-scale

0.618

High

612048

ITB5
Integrin beta-5

1

6

Small-scale

0.618

High

845954

DCC
Netrin receptor DCC

1

18

Small-scale

0.618

High

831947

IF2G
Eukaryotic translation initiation factor 2 subunit 3

2

2

Small-scale

0.611

High

845959

EI2BB
Translation initiation factor eIF2B subunit beta

2

2

Small-scale

0.611

High

845962

EIF3E
Eukaryotic translation initiation factor 3 subunit E

2

1

Small-scale

0.611

High

845969

RL10A
Large ribosomal subunit protein uL1

2

4

Small-scale

0.611

High

845975

MAPK3
MAP kinase-activated protein kinase 3

1

1

High-throughput

0.590

High

845994

MYO10
Unconventional myosin-X

1

4

Small-scale

0.589

High

845978

SIAH1
E3 ubiquitin-protein ligase SIAH1

2

1

Small-scale

0.586

High

445510

IF4E
Eukaryotic translation initiation factor 4E

2

2

Small-scale

0.584

High

845966

RS4X
Small ribosomal subunit protein eS4, X isoform

2

0

Small-scale

0.559

High

845986

BARD1
BRCA1-associated RING domain protein 1

1

13

High-throughput

0.555

High

845977

TRI67
Tripartite motif-containing protein 67

1

16

Small-scale

0.553

High

840015

CASP3
Caspase-3

1

1

Small-scale

0.552

High

846000

DP13A
DCC-interacting protein 13-alpha

1

3

Small-scale

0.552

High

845990

TBD2A
TBC1 domain family member 2A

1

1

High-throughput

0.541

High

582701

EZRI
Ezrin

1

8

Small-scale

0.536

High

845957

RS10
Small ribosomal subunit protein eS10

1

2

Small-scale

0.536

High

845967

RL23
Large ribosomal subunit protein uL14

1

1

Small-scale

0.536

High

845970

RL38
Large ribosomal subunit protein eL38

1

1

Small-scale

0.536

High

845971

ADA17
Disintegrin and metalloproteinase domain-containing protein 17

1

6

High-throughput

0.536

High

845973

EI2BA
Translation initiation factor eIF2B subunit alpha

1

2

Small-scale

0.536

High

845979

IF4E3
Eukaryotic translation initiation factor 4E type 3

1

2

Small-scale

0.536

High

845998

LHX3
LIM/homeobox protein Lhx3

1

4

High-throughput

0.536

High

845999

EI2BD
Translation initiation factor eIF2B subunit delta

1

2

Small-scale

0.536

High

845961

MAZ
Myc-associated zinc finger protein

1

1

Small-scale

0.523

High

421186

ALDOB
Fructose-bisphosphate aldolase B

1

0

High-throughput

0.518

High

482353

F16P1
Fructose-1,6-bisphosphatase 1

1

0

High-throughput

0.518

High

701956

TMOD1
Tropomodulin-1

1

0

High-throughput

0.518

High

627609

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

Small-scale

0.513

High

635765

PHOS
Phosducin

1

0

High-throughput

0.513

High

686013

RL13
Large ribosomal subunit protein eL13

1

0

Small-scale

0.513

High

845965

RS13
Small ribosomal subunit protein uS15

1

0

Small-scale

0.513

High

845968

RS24
Small ribosomal subunit protein eS24

1

0

Small-scale

0.513

High

845992

IF5A2
Eukaryotic translation initiation factor 5A-2

1

0

Small-scale

0.513

High

845981

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

3

High-throughput

0.494

High

389978

ALBU
Albumin

1

2

High-throughput

0.489

High

211547

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

1

Small-scale

0.481

High

673816

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

824035

RL13A
Large ribosomal subunit protein uL13

1

1

Small-scale

0.479

High

845963

IF4A1
Eukaryotic initiation factor 4A-I

1

3

Small-scale

0.479

High

845964

RS23
Small ribosomal subunit protein uS12

1

1

Small-scale

0.479

High

845974

IF4A2
Eukaryotic initiation factor 4A-II

1

3

Small-scale

0.479

High

845997

RRBP1
Ribosome-binding protein 1

1

4

High-throughput

0.470

High

593043

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.458

High

845958

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

0

Small-scale

0.458

High

845995

EI2BG
Translation initiation factor eIF2B subunit gamma

1

0

Small-scale

0.458

High

845996

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.457

High

845989

EIF2A
Eukaryotic translation initiation factor 2A

1

1

Small-scale

0.437

High

261607

CATL2
Cathepsin L2

1

0

High-throughput

0.282

High

845976

TSTD2
Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2

1

0

High-throughput

0.282

High

845980

TDRD7
Tudor domain-containing protein 7

1

0

High-throughput

0.282

High

845983

SFRP2
Secreted frizzled-related protein 2

1

0

High-throughput

0.282

High

845987

TRMO
tRNA

1

0

High-throughput

0.282

High

845988

HEMGN
Hemogen

1

0

High-throughput

0.282

High

845984

REEP6
Receptor expression-enhancing protein 6

1

0

High-throughput

0.279

Low

558967

LYL1
Protein lyl-1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025